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View Full Version : Poop 'Poop Transplants' May Combat Bacterial Infections (really)


DaFace
10-21-2012, 02:44 PM
Figured this would fit in well here.

http://news.yahoo.com/poop-transplants-may-combat-bacterial-infections-130609662.html

'Poop Transplants' May Combat Bacterial Infections
By Karen Rowan, MyHealthNewsDaily Managing Editor | LiveScience.com – Sat, Oct 20, 2012

"Poop transplants" are an effective way to treat people with one type of intestinal bacteria infection, a new study shows.

Researchers transplanted fecal matter from healthy people into the colons of people infected with the notoriously hard-to-treat Clostridium difficile bacteria, which causes severe, watery diarrhea. The researchers found that 46 out of 49 patients got better within a week of the treatment.

The transplant works because stool from healthy people, when mixed with warm water and delivered via a tube into patients' colons, helps re-establish the normal balance of bacteria in the intestine.

"C. diff is a serious infection — people die from this. With this treatment, the cure rate is close to 100 percent," said study researcher Dr. Mayur Ramesh, an infectious disease physician at Henry Ford Hospital in Detroit.

Among the 46 patients for whom the transplant was successful, four experienced a recurrence of their infection during the follow-up period. By contrast, studies have shown that infections recur in 25 to 30 percent of patients who receive the standard treatment for C. diff, which is a course of antibiotics, Ramesh said.

As of three months after the treatment, the patients had developed no complications or side effects as the result of their transplants, the researchers reported today at an infectious diseases research meeting in San Diego.

C. diff infections are linked to 14,000 deaths in the U.S. yearly, according to the Centers for Disease Control and Prevention. People at highest risk for the infection are older adults and those who take antibiotics. It's believed that antibiotics may disrupt the normal balance of bacteria species in the intestine, giving C. diff bacteria a chance to thrive.

Patients with C. diff infections are typically treated with the antibiotics metronidazole or vancomycin; however, these drugs don't work for everyone, the researchers said. In severe cases, patients may need surgery to remove the infected parts of their intestines.

In the study, researchers looked at patients whose average age was 65 and who were treated with fecal matter transplants over a two-year period at the study’s hospital. In most cases, the donor was the spouse or child of a patient, but in some cases, siblings, parents, or unrelated people donated fecal matter.

The patients were not much bothered by the possible ick factor of the treatment, Ramesh told MyHealthNewsDaily. "These patients, they suffer so much from their symptoms," he said. "When I tell them about this treatment, they say, 'wow, that makes sense, go ahead and do it.'"

No patients declined the treatment, he said.

Other studies have found a similarly high percentage of C. diff patients can be treated successfully with fecal tranplants. However, the new research differed from previous studies because about a third of the patients had severe C. diff infections. "These are the patients who may die, or need to have a section of their colon removed," Ramesh said. Other studies have focused on patients with recurring, but not severe infections, he said.

Four patients in the study died, including three whose C. diff infection had been successfully treated with the transplant. The deaths were unrelated to C. diff, the researchers said; all had cancer before starting the treatment.

While this study and others suggest that fecal matter transplants are effective, randomized controlled trials are considered the "gold standard" of evidence in medicine.

One such trial was recently approved to begin in the U.S. In that study, patients will be randomized into two groups: in one, patients will receive fecal matter from healthy donors, while in the control group, patients’ own fecal matter will be transplanted back into them, according to an article published in September in the journal Clinical Infectious Diseases.

Art Vader
10-21-2012, 02:53 PM
AKA The Chiefs upcoming off-season

Dave Lane
10-21-2012, 02:55 PM
OK thats disgusting

ClevelandBronco
10-21-2012, 02:57 PM
So, where do we donate?

ChiefsHawk
10-21-2012, 02:57 PM
ive had c-dif and that sh*t is serious business

milkman
10-21-2012, 02:58 PM
Uh.....this shit is a repost.

BigMeatballDave
10-21-2012, 03:01 PM
Shit research

DaFace
10-21-2012, 03:02 PM
Uh.....this shit is a repost.

Bringing in Cassel to replace Huard doesn't count.

BigMeatballDave
10-21-2012, 03:02 PM
So, where do we donate?

Not Arrowhead, it's full.

mlyonsd
10-21-2012, 03:06 PM
This should be the king of all poop threads.

KC Tattoo
10-21-2012, 03:10 PM
http://i940.photobucket.com/albums/ad250/baasaysthelamb/gifs%20and%20reaction%20imgs/themoreyouknowgif.gif

Ebolapox
10-21-2012, 03:11 PM
this is also being considered for those who have crohn's and the IBD spectrum of diseases. chronic inflammation is nothing to fuck with. I could give a long and detailed post on how important our gut microbiota are, but it would be a complete waste of time. needless to say, I'm sure we all give a crap, but some of you don't know shit from shinola. the number two reason threads fail on this BB is ignorance. Shiza!

loochy
10-21-2012, 03:14 PM
We replaced Cassel with Quinn last week and it didn't help. We replaced Carl with Pioli and nothing improved. Therefore, this method has been proven false.

Ebolapox
10-21-2012, 03:22 PM
We replaced Cassel with Quinn last week and it didn't help. We replaced Carl with Pioli and nothing improved. Therefore, this method has been proven false.

hey, climb off of that...STOOL.

theelusiveeightrop
10-21-2012, 03:22 PM
Two girls, one cup tried this. Didn't work.

Donger
10-21-2012, 03:34 PM
That's kind of a new take on giving someone shit.

JoeyChuckles
10-21-2012, 04:11 PM
Who are these "unrelated donors"? How does that conversation start?

Start Croyle
10-21-2012, 04:16 PM
Is this something you can get paid for, like how you can donate plasma for $20? I have a healthy diet with a lot of vegetables, wheat and beans. I would be an ideal donor if the quality of the transplanted product is important.

Munson
10-21-2012, 04:47 PM
This thread is full of shit!

listopencil
10-21-2012, 05:31 PM
AKA The Chiefs upcoming off-season

/thread

DenverDanChiefsFan
10-21-2012, 06:16 PM
Pics or GTFO...:eek:

GloryDayz
10-21-2012, 06:53 PM
Can you pick your doner? Just sayin...

Gonzo
10-21-2012, 07:38 PM
http://www.godlikeproductions.com/sm/custom/dmsjtqfn.jpeg

FAX
10-21-2012, 07:44 PM
Just went to that CostCo place and bought 8,000 ziplock baggie deals.

I'm prepared to begin saving lives.

FAX

GloryDayz
10-21-2012, 07:50 PM
Just went to that CostCo place and bought 8,000 ziplock baggie deals.

I'm prepared to begin saving lives.

FAX

Rep!

Goldmember
10-21-2012, 09:17 PM
Who are these "unrelated donors"? How does that conversation start?

Brother, can you spare a turd?

FAX
10-21-2012, 09:17 PM
Brother, can you spare a turd?

ROFL

FAX

FAX
10-21-2012, 09:18 PM
Poor bastards. Bedraggled ... lying sick in the gutter ... calling out in their weak voices ... begging for turds.

FAX

rockymtnchief
10-21-2012, 10:09 PM
FFS, If you can't shit/have to grunt to shit/shit clumps of moon rock....switch to Coors Lite.

ChiefsNow
10-21-2012, 10:16 PM
I don't give a shit.