The American Conference of Governmental Industrial Hygienists and the International Agency for Research on Cancer classify beryllium and its compounds as confirmed human carcinogens (classifications A1 and Group 1, respectively). These determinations are based on animal studies in which cancers were induced in laboratory animals dosed with beryllium and on human epidemiological studies of workers in beryllium plants that showed a slight increase in lung cancer incidence.

3.0 Controls

All beryllium work shall be controlled to minimize the number of workers and visitors exposed or potentially exposed and the opportunities for exposure. When beryllium needs to be used for an operation, controls shall be implemented in the following order of priority:

* Engineering controls.

* Administrative controls.

* PPE.

3.1 Chronic Beryllium Disease Prevention Program

LLNL's written program to implement the CBDPP [i.e., LLNL Chronic Beryllium Disease Prevention Program (UCRL-AR-144636, Rev. 1.1)], required by 10 CFR 850, has been approved by DOE Oakland. Specific actions are required by the following other ES

* Document 2.2, "Managing ES

* Document 3.3, "Facility Safety Plans and Integration Work Sheets with Safety Plans."

* Document 10.2, "LLNL Health Hazard Communication Program."

* Document 11.1, "Personal Protective Equipment."

* Document 12.2, "Ventilation."

* Document 12.4, "Work Enclosures and Local Exhaust Systems for Toxic and Radioactive Materials."

* Document 12.5, "High-Efficiency Particulate Air (HEPA) Filter System Design for LLNL Applications."