The following actresses all were offered and declined the lead role in Gravity before Bullock accepted:
Angelina Jolie (twice), Natalie Portman, Jennifer Lopez, Rachel Weisz, Marion Cotillard, Carey Mulligan, Blake Lively, Scarlett Johansson, and Olivia Wilde.
Oops. They are all probably kicking themselves now.
<ptp> how many emo kids does it take to change a lightbulb?
<Willy> HOW MANY?!
<ptp> none they just sit in the dark and cry