The following actresses all were offered and declined the lead role in Gravity before Bullock accepted:
Angelina Jolie (twice), Natalie Portman, Jennifer Lopez, Rachel Weisz, Marion Cotillard, Carey Mulligan, Blake Lively, Scarlett Johansson, and Olivia Wilde.
Oops. They are all probably kicking themselves now.
<WarMoose> Think about how stupid the average person is. Now realize that half of them are dumber than that.
<Chunda> Why half?