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Old 03-22-2014, 08:36 PM   #702
Cephalic Trauma Cephalic Trauma is offline
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Quote:
Originally Posted by BigCatDaddy View Post
Some of the studies are a joke, especially overseas and like I mentioned there are some shady companies so I understand that.

There just isn't enough money in the supplement industry to do those long sustained trials and if you tried some other company is bringing it to the market without worrying about do them. I'm not sure how much good it would do though. They can't even conclusively determine if TRT is "safe". For ever study that says it isn't there is a study that says it is. And then is TRT worse than having Low T?
In some cases, yes. But we are very careful about how we treat older guys with TRT, and that's a clinical cost-benefit conversation that physicians have with their patients. All urologists know a **** ton more about that than I, though.

The idea behind methyl is that it is chemically altered at the 17 alkyl position to inhibit metabolism and allow it to be effective orally. The problem, however, is that 17-alkyl modification is extremely toxic to hepatocytes. We don't have this problem with the creams and depo preps because they are unaltered testosterone and testosterone esters that don't have the same modification. Thus, methyltestoterone is clinically useless.

However, back to the supplement industry, the money is probably there. The incentive, however, is not. That stems mainly from their average consumer not giving a ****.
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