For most activities it's Ghorn for me. I got lucky and scored one early and I have used it to save my own ass countless times.
The primary rocket does a ton of damage and the wolf pack rounds basically double the damage. A buddy an I often two man normal Crota and since he doesn't have a Ghorn he's in-charge of the sword. Two rockets is all that it takes to bring down Crota's shield.
I can't think of many situations where I would take some other exotic over it (except for Crucible).
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