I like NPR's All Song's Considered. The host has different musicians on as guest DJs, and they also broadcast concerts and seasonal music previews. I've picked up a lot of good stuff from that podcast.
I also like KCRW's The Treatment. The host used to be a New York Times movie critic. He has on different people in the movie industry. Sometimes the guests are lame so the show sucks, but when he has a good guest on its worth listening to because he's a good interviewer.
Sometimes you eat the bear and sometimes, well, he eats you.