Touristy Stuff....(not big into it but I'm sure I can find more if you want)
Coit Tower
Lombard St(famous crooked road).
Palace of Fine arts and the presido
Wine drinker?
Hit up napa or sonoma(sonoma tends to be cheaper).
Always a good chance of rain be prepared. Fairly cold for SF this year but not that bad for those born in real weather.
There are some great restaurants depending upon what you want.
Some good museums De Young, Asian Art. Been too busy but I've heard the California Academy of sciences is great.
The question is what do you want to do? Let me know and I can talk to some people and see what's available.