Thread: Other Sports Ryan Braun tests positive for PED
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Old 02-24-2012, 12:40 PM   #269
BigCatDaddy BigCatDaddy is offline
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Quote:
Originally Posted by alnorth View Post
His "insanely high" TE ratio was 20-1. From what I've read, its pretty high and you don't see it often, but it is not an impossible ratio at all.
Yeah, I found this little nugget. Basically if you are over 1100NG you are probably using synthetic test. The average male being about 400-500.

However, theres a little twist to the story! Various studies reveal serious weaknesses in the T/E ratio test used by various anti-doping organizations as a biomarker. One of the reports published in the Journal of Clinical Endocrinology & Metabolism successfully argues that the production of TG from testosterone is primarily controlled by an enzyme (UGT2B17) produced by a specific gene that has many common variants coding for enzymatic variants with different levels of activity. So, wildly different testing results can be expected with the intake of same doses of testosterone! In lieu of this, the validity of T/E based testing has widely been debated and alternate methods of hormone testing have been suggested.



Read more: http://www.testcountry.org/how-stero...#ixzz1nKW9foWu
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