It all depends on the dungeon shards you acquire in end game. If you are fire based, lightning based, etc and there is a boss with 50% fire, lightning, etc resist you just can't go. Unless you have more than 2 people in your group. I feel like all endgame shards will have some kind of elemental debuff. Might as well spend points in as many resist talents as you can. That's what I'm doing.