Ya you have to run. I waited the the big prick came first, then I shot the fire extinguisher. Then hit him with a molotov and ran. Killed the remaining clickers and infected with shotgun and molotovs. I ran and let the big bloater walk upstairs. I followed proceeding to hit him with a nail bomb and 4 or so shots with my shotgun and he died. It was a bitch and I was on normal. I'm playing with a friend on survivor and honestly have no clue how I'll do that part. Survivor is really fun but hard because you have no listening ability and limited ammo/resources.
Adopt a Chief: Jamaal Charles