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Originally Posted by Dick Pull
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I don't know if HFCS directly causes obesity but those are rodent studies. Rats are not furry little humans and there are a lot of things that can affect rats that don't affect humans, and vice versa.
Rat studies are a good starting point but you need double-blinded human studies to know for sure.
IMO, the worst thing about HFCS is that it is very cheap, so it ends up in everything to add more palatability, which can motivate people to overeat. Plus, it adds extra calories that aren't necessary.