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Originally Posted by Detoxing
I've never taken Meth or Heroin or any of that shit (i've seen enough from others abusing it) but i've done Ecstasy a few times.
When the pill initially kicks in, i hate it. I hate the loss of control of myself. It's too overwhelming. However, the come down is absolutely euphoric. It's a trip. I can't explain it.
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The "come down" I'm referring to is the serotonin crash that occurs days later.
http://www.neurosoup.com/schedule1/mdmamainpage.htm
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Many users describe an MDMA back-end, or period of feeling depressed and drained after use. Curran & Travill (1997) concluded that, "Weekend use of MDMA may lead to depressed mood mid-week." They continued to explain that "...the results of this study imply that MDMA use at the weekend is associated with subsequent low mood mid-week and with impaired attentional function. It is not clear to what extent this may reflect a temporary serotonergic depletion, a more serious serotonergic neurotoxicity or a psychological consequence of the acute `high’ mood induced by weekend MDMA use." Nutrients that may help with the MDMA back-end (to be taken the week after use) are listed in the table below:
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With a lot of "weekend" party drugs, there are similar reactions. A lot of people don't even know why they're depressed or not feeling good during the middle of the week, and it's often a result of the partying they did on the weekend.