Uhm, yeah, that can happen, although as you mention the exercise helps a lot. Eating better and sleeping like a regular person seems to help, too.
My job isn't a whole lot different than gaming binges, either.
Basically it's like anything else: if you go to extremes there will be bad side effects. I can do this for a weekend. I won't play like this after release though. At least not after the first couple of weeks (which will be crazy...). It'll balance out to a few hours a night eventually.
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