Here are my thoughts on the female characters...
The "strongest" of the group, (IMO anyway), would be Lori and I doubt she will get killed-off. Yeah, she can be annoying at times, but she has a mission to keep her boy and unborn child alive.
Maggie busted out of her shell quite a bit after the barn incident. I think she will become a strong leader in the group and be able to hold her own against the Walkers.
Andrea tries to appear tough, but with her giving up at the CDC building that showed her true weakness. Plus, now she's overstepping her bounds w/ everyone, (especially w/ the suicidal girl incident). I have a feeling she's going to stray from the group and get mauled by zombies.
I thought Sophia's mom was pretty weak to begin with and now she's in shambles over the death of her girl. I'm guessing she will probably chew a bullet.
As far as suicidal girl, she annoys the crap out of me and needs to get nibbled on by a bunch of zombies.