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Old 04-15-2014, 09:12 PM  
Tribal Warfare Tribal Warfare is offline
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BREAKING NEWS!: Casual marijuana use linked with brain abnormalities

Casual marijuana use linked with brain abnormalities, study finds

Casual marijuana use may come with some not-so-casual side effects.

For the first time, researchers at Northwestern University have analyzed the relationship between casual use of marijuana and brain changes – and found that young adults who used cannabis just once or twice a week showed significant abnormalities in two important brain structures.

The study’s findings, to be published Wednesday in the Journal of Neuroscience, are similar to those of past research linking chronic, long-term marijuana use with mental illness and changes in brain development.

Dr. Hans Breiter, co-senior study author, said he was inspired to look at the effects of casual marijuana use after previous work in his lab found that heavy cannabis use caused similar brain abnormalities to those seen in patients with schizophrenia.

"The interaction of marijuana with brain development could be a significant problem."

- Dr. Hans Breiter, co-senior study author

“There were abnormalities in their working memory, which is fundamental to everything you do,” Breiter, a professor of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine, told FoxNews.com. “When you make judgments or decisions, plan things, do mathematics – anything you do always involves working memory. It’s one of the core fundamental aspects of our brains that we use every day. So given those findings, we decided we need to look at casual, recreational use.”

For their most recent study, Breiter and his team analyzed a very small sample of patients between the ages of 18 and 25: 20 marijuana users and 20 well-matched control subjects. The marijuana users had a wide range of usage routines, with some using the drug just once or twice a week and others using it every single day.

Utilizing magnetic resonance imaging (MRI), the researchers analyzed the participants’ brains, focusing on the nucleus accumbens (NAC) and the amygdala – two key brain regions responsible for processing emotions, making decisions and motivation. They looked at these brain structures in three different ways, measuring their density, volume and shape.

According to Breiter, all three were abnormal in the casual marijuana users.

“For the NAC, all three measures were abnormal, and they were abnormal in a dose-dependent way, meaning the changes were greater with the amount of marijuana used,” Breiter said. “The amygdala had abnormalities for shape and density, and only volume correlated with use. But if you looked at all three types of measures, it showed the relationships between them were quite abnormal in the marijuana users, compared to the normal controls.”

Because these brain regions are central for motivation, the findings from Northwestern help support the well-known theory that marijuana use leads to a condition called amotivation. Also called amotivational syndrome, this psychological condition causes people to become less oriented towards their goals and purposes in life, as well as seem less focused in general.

Given these eye-opening results, Breiter said that more research is needed to look into marijuana’s effects on the brain – even in those who use the drug only once or twice a month.

“We need to see what happens longitudinally,” Breiter said. “What happens as you follow people over time? What happens if they stop using – do these bad effects continue? What happens if you can intervene early?...My worry is we haven’t studied this compound and here we are looking to change legislation on it.”

Although Breiter’s team members did not examine the patients’ cognitive symptoms, they do believe that the brain abnormalities seen in their study could lead to substantial effects on brain development and behavior, especially given the young ages of the participants. Breiter also acknowledged the problems of analyzing a very small study sample – but said that their findings should still serve as a wake-up call to others.

“This study is just a beginning pilot study, but at the same time, the results that came out are the same as a canary in a coal mine,” Breiter said. “...The interaction of marijuana with brain development could be a significant problem.”
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Old 04-16-2014, 02:09 PM   #166
Katipan Katipan is offline
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No. I've never been sprayed but I know that it's stinky regardless.
Does the smell of your own farts bother you?
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Old 04-16-2014, 02:10 PM   #167
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Does the smell of your own farts bother you?
Yes.
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Old 04-16-2014, 02:12 PM   #168
BigMeatballDave BigMeatballDave is offline
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Donger is a tad prissy.

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Old 04-16-2014, 02:13 PM   #169
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Does the smell of your own farts bother you?
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Old 04-16-2014, 02:14 PM   #170
BigMeatballDave BigMeatballDave is offline
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I can't even smell it without thinking of dry heaving.
Exactly how I feel about Jager.
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Old 04-16-2014, 02:15 PM   #171
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I can sip quality vodka neat all night. But how do people drink scotch? I can't even smell it without thinking of dry heaving.


I love Scotch straight up.
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Old 04-16-2014, 02:16 PM   #172
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Exactly how I feel about Jager.
For me, that drink is MD 20/20.

Probably has something to do with the 24 hours of vomiting I once experienced though...
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Old 04-16-2014, 02:17 PM   #173
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And people willingly smoke that?
So much so that they've created a whole industry to it's refinement and production. ( He posts as he eyes the clock as it ticks toward 3:15......Yeah it's 4:20 somewhere.)
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Old 04-16-2014, 02:21 PM   #174
BigMeatballDave BigMeatballDave is offline
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For me, that drink is MD 20/20.

Probably has something to do with the 24 hours of vomiting I once experienced though...
The thought of getting drunk right now just turns my stomach. Haven't been drunk since a friend's bachelor party.

In 1992! LOL
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Old 04-16-2014, 02:22 PM   #175
Nzoner Nzoner is offline
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Exactly how I feel about Jager.
Same here haven't touched that shit in 8+ years
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Old 04-16-2014, 02:25 PM   #176
Katipan Katipan is offline
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I enjoy different opinions. Vigorous debate always helps me clarify my positions internally. I like the fact that we don't all think the same.

But stop ****ing talking shit about Jäger.
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Old 04-16-2014, 02:27 PM   #177
BigMeatballDave BigMeatballDave is offline
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I enjoy different opinions. Vigorous debate always helps me clarify my positions internally. I like the fact that we don't all think the same.

But stop ****ing talking shit about Jäger.
I really hate licorice. Jager smells like it.

Vomit.

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Old 04-16-2014, 02:27 PM   #178
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Old 04-16-2014, 02:34 PM   #179
Nzoner Nzoner is offline
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Originally Posted by Katipan View Post
I enjoy different opinions. Vigorous debate always helps me clarify my positions internally. I like the fact that we don't all think the same.

But stop ****ing talking shit about Jäger.
I enjoy vigorous debate as well and after a night I had with Jager will never stop talking shit on it.

And no I am not telling the story on the internet.
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Old 04-16-2014, 02:57 PM   #180
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I really hate licorice. Jager smells like it.

Vomit.

Yeah, Jager is turruble. Gin is just as bad.
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