Originally Posted by 'Hamas' Jenkins (Post 15194265)

There are a lot of variables in a drug test. He can still have it in his system and not have enough of the metabolite to spike a positive test. This can be exacerbated by other drugs or supplements one takes. Clonazepam is a CYP3A4 substrate, of which there are many inducers (grapefruit, protease inhibitors, cimetidine, cyclosporine, macrolides, amiodarone, azole antifungals, non-DHP calcium channel blockers). Inducers can cause a person to clear the drug much faster than they would under normal physiological conditions.

Have your pills recently changed color or shape? It's possible the pharmacy gave you the wrong medication--for example Clonidine instead of Clonazepam. If not, the pharmacy would be able to tell you the lot number of the mediation and the supplier. Should others have similar issues, they would need to institute a recall due to adulteration, as clonazepam is primarily used for seizure control, and prompt withdrawal will cause exacerbations and potentially status epilepticus.

Originally Posted by 'Hamas' Jenkins (Post 15194265)

There are a lot of variables in a drug test. He can still have it in his system and not have enough of the metabolite to spike a positive test. This can be exacerbated by other drugs or supplements one takes. Clonazepam is a CYP3A4 substrate, of which there are many inducers (phenobarb, carbamazepine, oxcarbazapine, rifampin, phenytoin, smoking). Inducers can cause a person to clear the drug much faster than they would under normal physiological conditions.

Have your pills recently changed color or shape? It's possible the pharmacy gave you the wrong medication--for example Clonidine instead of Clonazepam. If not, the pharmacy would be able to tell you the lot number of the mediation and the supplier. Should others have similar issues, they would need to institute a recall due to adulteration, as clonazepam is primarily used for seizure control, and prompt withdrawal will cause exacerbations and potentially status epilepticus.

Originally Posted by htismaqe (Post 15194627)

1.5mg isn't a low dose.

Originally Posted by dlphg9 (Post 15194846)

Immunoassay methodology isn't very reliable when it comes to UDS. They have can easily have false positives because they are picking up the structure of the molecule and if someone has taken something similar in structure then it may flag as positive. Im not sure why they don't pick up clonazepam, but I had read that they have false negatives ~30% of the time with benzos.

See if they can just call into Quest and have then do the mass spectrometry for Benzos and that should pick it up.

Originally Posted by Hog's Gone Fishin (Post 15194406)

Oh, you beat me to it. I was going to post the same thing.

Originally Posted by scho63 (Post 15196578)

How to Read your Blood Test Results

http://www.amarillomed.com/howto

Originally Posted by dlphg9 (Post 15194846)

Immunoassay methodology isn't very reliable when it comes to UDS. They have can easily have false positives because they are picking up the structure of the molecule and if someone has taken something similar in structure then it may flag as positive. Im not sure why they don't pick up clonazepam, but I had read that they have false negatives ~30% of the time with benzos.

See if they can just call into Quest and have then do the mass spectrometry for Benzos and that should pick it up.