How will the show end? GRRM said it would be "bittersweet."
So I'm going with...White walkers destroy the north, kill Sansa. Dany and her dragons die stopping them at King's landing. Arya kills everyone on her shit list, but dies killing Cersei. Jon is the shitty King Westeros is left with to get through winter.
Last line from Tyrion "Well, I guess you're the King now. Enjoy ruling what's left of Westeros. I'm going to get drunk."
