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Originally Posted by Hammock Parties
What would happen if you pumped someone full of multiple antibiotics for 10 days straight?
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First, you often need to separate the bags so they don't precipitate and tear up your vasculature as they are infused.
After that, depends on the antibiotic. Vancomycin and aminoglycosides, which he's almost certainly getting, are nephrotoxic , so you have to monitor kidney function. Other antibiotics for resistant staph infections like linezolid can cause bone marrow suppression after two weeks and serotonin syndrome if given with certain meds. Daptomycin can cause breakdown of your muscle tissue. Many others can destroy your GI flora and increase your chances of a c. diff infection.
Beyond that, more than 1-2 antibiotics for certain susceptibility (gram positive, negative) is wholly unnecessary and only increases side effects.
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"When the Know-Nothings get control, it will read 'all men are created equal, except negroes, and foreigners, and Catholics.' When it comes to this I should prefer emigrating to some country where they make no pretense of loving liberty – to Russia, for instance, where despotism can be taken pure, and without the base alloy of hypocrisy.”--Abraham Lincoln
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