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Originally Posted by O.city
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Remdesevir is the best shot. There is thought that IL-6 contributes to mortality in sepsis. Tocilizumab's MOA is inhibition of IL-6, but as a biologic it is going to be far too difficult to scale production and would only help sequelae. Chloroquine and Plaquenil have been used in limited cases, and are likely working by reduction of inflammatory response.
The protease inhibitors could work if the viral protease is similar to HIV's, but all work has been in vitro at this point. Much different than trying in humans.
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"When the Know-Nothings get control, it will read 'all men are created equal, except negroes, and foreigners, and Catholics.' When it comes to this I should prefer emigrating to some country where they make no pretense of loving liberty – to Russia, for instance, where despotism can be taken pure, and without the base alloy of hypocrisy.”--Abraham Lincoln
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