Quote:
Originally Posted by candyman
Didn't someone say earlier in this thread chloroquine phosphate was only being used as an anti-inflammatory, not as a potential cure? This is why I dont believe anything I read...pretty much anywhere.
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Hydroxychloroquine is normally used as a DMARD for rheumatoid arthritis. It reduces cytokine production (inflammation), which reduces autoimmune destruction of the joints.
If the antiautophagy aspects of the drug result in less cell destruction (and potentially viral release from infected cells--I'm speculating here) then you might reduce the circulating viral load.
The exact mechanism of chloroquine/hydroxycholoroquine is still somewhat unknown.
Chloroquine has never been used as an antiviral. From its known mechanism, it may help someone ride out the storm, but some heretofore unknown MOA is possible, but unlikely
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"When the Know-Nothings get control, it will read 'all men are created equal, except negroes, and foreigners, and Catholics.' When it comes to this I should prefer emigrating to some country where they make no pretense of loving liberty – to Russia, for instance, where despotism can be taken pure, and without the base alloy of hypocrisy.”--Abraham Lincoln
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