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Originally Posted by AustinChief
Wtf are you talking about? We are talking about what numbers show whether or not Texas's reopening is causing a spike in Covid cases. The raw number of cases confirmed by testing is not a good indicator because of the increase in testing. Deaths in the other hand(given a lag time) are a much better indicator.
Your misleading fear mongering comment has zero to do with what we were discussing. If you choose to defend your comment please provide specific data and research on how many people as a percentage have proven permanent damage due to Covid-19. Make sure it is broken down by age please. Not sure how much I'm supposed to care about a 98 year old with "permanent" damage.
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It's a worthwhile question with muddy data at this point. Most of the analysis are cohort studies from patients that have been hospitalized, and thus have severe disease. Also, patients can present with multiple comorbidities.
As one would expect, older patients tend to have more severe effects, but it's also early to assume permanent dysfunction. However, there are markers of damage in a number of bodily systems
Cardiac injury in Wuhan: 19.7% of hospitalized patients had elevated cardiac enzymes indicative of myocardial damage. Those patients were older (mean age 74) than those without (60). Roughly half of patients with cardiac injury survived.
https://jamanetwork.com/journals/jam...?resultClick=1
Neurological manifestations in Wuhan: Approximately 36% of admitted patients were found to have some degree of CNS, skeletal, or PNS manifestation. Again, severity of illness and age were correlated more strongly with the likelihood of these issues. As this is a broad constellation of issues, it's important to delineate specific examples: acute cerebrovascular disease, like an ischemic stroke, happened in 2.8% of patients, whereas skeletal muscle injury happened in around 11% of patients, and alterations in taste and smell were closer to 5-6%
https://jamanetwork.com/journals/jam...rticle/2764549
Lung Damage:
SARS and MERS caused permanent lung damage in around 1/3 of cases. It's hard to know exact numbers for COVID-19 at this point, but a substantial number of discharged patients showed indications of lung damage on CT.
https://pubs.rsna.org/doi/full/10.11...iol.2020200843
94% (66/70) of patients who were discharged from hospital at the end of the study still had mild to substantial residual lung abnormalities on their last CT scans. The main pattern of those lung abnormalities was ground-glass opacity. A most recent publication reported 4 discharged cases who had positive SARS-CoV-2 RT-PCR results again 5-13 days after discharging(22). Thus, follow-up monitoring of patients might still be necessary
GGOs can resolve and they can be indicative of long-term damage to the alveoli. It's too soon to know.
Of course, more severe patients develop ARDS, and although many survive, ARDS in ICU patients leads to longterm cognitive impairment approximately 1/5th of the time (Paywalled for you, most likely:
https://journals.lww.com/ccmjournal/...s__Risk.8.aspx)
Clotting Disorders:
Patients with more severe disease will be more likely to present with a coagulopathy. Around 30% of hospitalized patients in France were found to have a PE if they weren't in ICU, compared to 72% of those who were (sample sizes were low; n=32 for ICU, n=72 for not, but the differences are enough for a p < 0.001) Those that have a DVT, PE, or stroke will need to remain on anticoagulant therapy for at least six months afterwards, which carries its own burdens and risks.
https://pubs.rsna.org/doi/10.1148/radiol.2020201561
As for the ultimate breakdown on all subgroup analyses, that will take time, but it is clear that this is a disease that attacks multiple organ systems, often through coagulopathies. As one would expect with any other disease, the older and sicker you are, the worse your prognosis, but this is not merely an issue affecting the elderly.