Quote:
Originally Posted by 'Hamas' Jenkins
There is no data to support giving it early at this point. When dealing with evidence-based medicine, you need evidence. Given that no trials have come forth establishing a protective mechanism for hydroxychloroquine either to prevent infection or early in infection, saying that it needs to be given early is just conjecture, especially when you lack a control group to compare it against.
Antivirals in general will help more when started sooner than later (Tamiflu being a great example), but it doesn't mean that the help drops to zero once you have a moderate infection.
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I get what you are saying, but your second paragraph points to what they have been saying that it being an antiviral, the key is the sooner the better. My bigger point is why waste studies on claims that most doctors that are advocates have largely not made? Focus on proving or disproving the point-in-time that giving the drug may help.