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Old 06-24-2020, 01:54 PM   #36024
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Quote:
Originally Posted by petegz28 View Post
Well I don't know what to tell you but it was all over the news.

Maybe you should call someone?

Could Statins Reduce the Severity of COVID-19?
https://www.the-scientist.com/news-o...ovid-19--67629

Major study finds common steroid reduces deaths among patients with severe Covid-19
https://www.statnews.com/2020/06/16/...vere-covid-19/


Just read an article reviewing the dexamethasone report

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Clinical Take Home Point:*The findings of this well done randomized controlled trial indicate that in patients with COVID-19 pneumonia, that dexamethasone improves 28d mortality compared to placebo in patients requiring IMV (NNT = 8.5) and those patients requiring oxygen therapy (NNT = 29).* There was no benefit to patients not requiring oxygenation support and even a signal for harm.* It is important to remember this is a preprint, preliminary report, which is better than a press release. At this time, in patients requiring any oxygen therapy, HFNC, NIV, IMV, or ECMO I would recommend dexamethasone until further evidence disproves this benefit.

***************

So clinical improvement in mortality for patients on oxygent

Number needed to treat is 29 patients on oxygen
Number needed to treat is 8.5 patients on a ventilator.

Cool study.

I was just commenting on the fact that steroids are very commonly used in the ICU for respiratory conditions.
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