02-09-2021, 05:21 PM
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#51517
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Sometimes it's black and white
Join Date: Nov 2004
Location: California
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The South Africa and Brazil variants, which are the most concerning for immunity, share several mutations, including a key one called E484K. These mutations change the shape of the virus’s spike protein, making it less recognizable to the immune system. In South Africa, the variant is reinfecting some people who had COVID-19 before. On Sunday, the country even paused its rollout of the AstraZeneca vaccine after data came to light suggesting that it does not protect against mild or moderate disease from the new variant. And the Johnson & Johnson and Novavax vaccines, which were trialed in parallel in multiple countries, also seem less effective in South Africa—falling from 72 to 57 percent efficacy and 89 to 49 percent efficacy, respectively. In Brazil, the region around Manaus is experiencing a huge second wave of COVID-19 despite high levels of previous immunity from a first wave last year. The new variant in Brazil may be responsible.
https://www.theatlantic.com/health/a...ccines/617973/
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