Quote:
Originally Posted by lawrenceRaider
The dominant variant, B5, doesn't care about prior infection immunity from even the B3 variant or vaccination immunity.
Just had a bunch of coworkers who went to a convention in Florida who all had four shots come back really sick with COVID.
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That's not entirely true..
https://www.medrxiv.org/content/10.1....11.22277448v1
Quote:
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Effectiveness of a previous pre-Omicron infection against symptomatic BA.4/BA.5 reinfection was 15.1% (95% CI: -47.1-50.9%), and against any BA.4/BA.5 reinfection irrespective of symptoms was 28.3% (95% CI: 11.4-41.9%). Effectiveness of a previous Omicron infection against symptomatic BA.4/BA.5 reinfection was 76.1% (95% CI: 54.9-87.3%), and against any BA.4/BA.5 reinfection was 79.7% (95% CI: 74.3-83.9%). Results using all diagnosed infections when BA.4/BA.5 dominated incidence confirmed the same findings. Sensitivity analyses adjusting for vaccination status confirmed study results. Protection of a previous infection against BA.4/BA.5 reinfection was modest when the previous infection involved a pre-Omicron variant, but strong when the previous infection involved the Omicron BA.1 or BA.2 subvariants.
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Qatar is an interesting study though. Their population is quite young. This may not translate well to everywhere else.