We had a hard time covering Cook as a receiving threat out of the backfield in our first game against the Bills. I think with Tranquill back and Bolton playing better post-injury, Spags will have an easier time taking that away, especially after seeing it on tape.
The Bills have a strong running game, and I would expect them to rely heavily on it, especially if they're playing with a lead.
I think if you're a Bills coach, you probably like the idea of long, sustained, run-focused drives that keep your injured defense on the sideline while somewhat neutralizing Allen's tendency to throw interceptions. They're an effective tush-push team as well, so I'd expect some 3rd down runs intentionally creating those 4th and short situations.
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