With Manning, I think you have to get pressure on him AND do something in the secondary such as keep the receivers from getting off the line or disguising the coverage. If you only have pressure he'll hit the hot routes. If you only disguise your coverage, he'll wait until one of his 5 receivers becomes open. You really have to play complete defense in the passing game, and defend the run. That's what makes the Colts so tough to contain.
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