Landis gives positive drugs test

The Poz · 07-27-2006, 08:24 AM

http://news.bbc.co.uk/sport2/hi/othe...ng/5221122.stm

Landis gives positive drugs test

Tour de France winner Floyd Landis has given a positive drugs test.
The American, who claimed victory in the Tour de France on Sunday, has tested positive for the male sex hormone testosterone.

More to follow.

It isn't football, but it makes me laugh how stupid some people are.

**cdcox** · 07-27-2006, 08:36 AM

The dopers are ruining cycling. Most of the favorites got thrown out before the race even started for doping.

hawkchief · 07-27-2006, 08:40 AM

Who was 2nd in the Tour DF? Guess they will become the champ now, eh? After all of the tests Lance Armstrong unerwent for the past 8 years, if this is true, how in the world did Landis expect to get away with this? Just plain stupid.

**Mr. Kotter** · 07-27-2006, 08:44 AM

Testosterone, eh?

I've always wondered, how do they "test" for doping for something your body produces naturally. I mean, my 'testosterone' levels are off the chart....and I certainly don't "dope."

Anyone know?

**Donger** · 07-27-2006, 08:46 AM

Steroid profiling has become an additional tool in dope control to detect changes in the normal pattern of excreted steroids. These changes may be the result of the misuse of testosterone, a precursor (androstenedione) or an active metabolite of testosterone (dihydrostestosterone) and/or long-term misuse of synthetic anabolic steroids.

Testing for testosterone administration has been routinely carried out by analysis of the ratio of testosterone glucuronide to epitestosterone glucuronide, usually known simply as the T/E ratio (Donike M. et al, 1985).

Considerations have varied slightly over the years and the present criterion for suspicion of testosterone administration is an abnormally elevated T/E ratio in urine. For some sport bodies the criterion is when the value exceeds the range normally found in humans and thought to be consistent with normal endogenous production. For other bodies, the rule is based on a ratio higher than the usual population (cut-off 6:1) but they accept the obligation to perform additional research in order to exclude the small percentage of people having high T/E ratios due to physiological or pathological conditions (Donike M. et al., 1993; Baezinger J. et al., 1994; Kicman A.T. et al., 1990).

Evidence has accumulated in recent years that T/E ratios are relatively stable in a given subject. Work carried out by different authors shows that deviations from a normal baseline value for a given individual should be the starting point for a suspicion of testosterone administration. It has also been shown that there exist, at least, two different classes of "normal" population, one with T/E values around 1-2 and another with T/E values of around 0.2-0.3, the latter mainly concentrated among the Mongoloid race group (Park J. et al., 1990; de la Torre X. et al., 1997).

Several authors have studied the effects of testosterone administration on many parameters and they have reached the conclusion that, if suitably chosen, some of these parameters may be highly indicative. Among the more interesting, there is the high increase in the testosterone/17 hydroxy-progesterone (T/17OHP) ratio and in the testosterone/luteinizing hormone (T/LH) ratio. The effects are based on the negative feedback of testosterone, both the release of LH by the hypophysis and the amount of some of its synthetic precursors present in the body, such as 17OHP.

Testosterone is usually administered as testosterone enanthate or as one of many other esters. These compounds were supposed to hydrolyse rapidly and completely in the body to release free testosterone. Modern methodology now allows us to determine that small amounts remain in the body for a long time. The finding of such compounds (exogenous: not existing in our body) in the blood would be indicative of testosterone administration (de la Torre X., et al., 199.).

It is possible to establish a list of generally accepted scientific facts that should be the basis for a rational approach to the problem of detection and confirmation of cases of testosterone doping. Those premises can be listed as follows:

1. T/E ratio in urine is fairly stable in a given individual

2. External testosterone administration disturbs some selected parameters such as T/17OHP in blood plasma and T/E in urine. The T/LH ratio both in blood plasma and urine is also affected. Many other markers have been studied in both plasma and urine but they have offered less definitive results.

3. The finding of esters of testosterone in blood plasma demonstrates testosterone administration.

**cdcox** · 07-27-2006, 08:47 AM

Quote:

Originally Posted by Mr. Kotter

Testosterone, eh?

I've always wondered, how do they "test" for doping for something your body produces naturally. I mean, my 'testosterone' levels are off the chart....and I certainly don't "dope."

Anyone know?

The anti-doping people have ranges of normal levels based on thouands of samples. He exceeded the range.

**Donger** · 07-27-2006, 08:49 AM

I'd imagine that Phonak will ask that his B sample be tested.

Either way, this sucks.

hawkchief · 07-27-2006, 08:52 AM

Way to embarrass your country, Landass!

**Mr. Kotter** · 07-27-2006, 08:53 AM

Thanks, cdcox

Quote:

Originally Posted by Donger

I'd imagine that Phonak will ask that his B sample be tested.

Either way, this sucks.

Yup.

http://sports.espn.go.com/oly/tdf200...ory?id=2531225

Phonak: Landis had positive test after Stage 17

ESPN.com news services

LONDON -- Tour de France champion Floyd Landis tested positive for high levels of testosterone during the race, his Phonak team said Thursday on its Web site. Phonak said Landis would ask for an analysis of his backup "B" sample "to prove either that this result is coming from a natural process or that this is resulting from a mistake."
The statement came a day after the UCI, cycling's world governing body, said an unidentified rider had failed a drug test during the Tour. The Swiss-based Phonak team said it was notified by the UCI on Wednesday that Landis' sample showed "an unusual level of testosterone/epitestosterone" when he was tested after stage 17 of the race last Thursday. Landis made a remarkable comeback in that Alpine stage, racing far ahead of the field for a solo win that moved him from 11th to third in the overall standings. He regained the leader's yellow jersey two days later. "The team management and the rider were both totally surprised of this physiological result," the Phonak statement said. Phonak said Landis would ask for an analysis of his backup "B" sample "to prove either that this result is coming from a natural process or that this is resulting from a mistake." Landis has been suspended by his team pending the results. If the second sample confirms the initial finding, he will be fired from the team, Phonak said. Landis failed to show up for a one-day race in Denmark on Thursday, a day after missing a scheduled event in the Netherlands. Dutch news agency ANP quoted his teammate Koos Moerenhout as saying that Landis had pain from his hip problem and had gone to see his doctor in Germany. He plans to have hip replacement surgery this fall to ease pain in the arthritic joint still aching from a 2003 crash during a training ride. "We were told by the other two riders that he couldn't join because he was traveling with team manager [John] Lelangue to his doctor in Germany," event organizer Theo van der Westerlaken said. "That's all we know." Landis did take part in a criterium race Tuesday in Stiphout, Netherlands, winning the event. Landis won the Tour de France on Sunday, keeping the title in U.S. hands for the eighth straight year after Lance Armstrong's record seven victories. On the eve of the Tour's start, nine riders -- including pre-race favorites Jan Ullrich and Ivan Basso -- were ousted, implicated in a Spanish doping investigation. The Associated Press and Reuters contributed to this report.

**Donger** · 07-27-2006, 08:55 AM

Quote:

Originally Posted by hawkchief

Way to embarrass your country, Landass!

Easy. False positives aren't that rare.

I hope that's the case here.

**Saulbadguy** · 07-27-2006, 08:55 AM

Big deal. Lance did it. This guy did it. Noone really cares about cycling.

DiaperBoy27 · 07-27-2006, 08:56 AM

is the source french?

**Donger** · 07-27-2006, 08:57 AM

Quote:

Originally Posted by Mr. Kotter

Thanks, cdcox

Yup.

http://sports.espn.go.com/oly/tdf200...ory?id=2531225

Phonak: Landis had positive test after Stage 17

ESPN.com news services

LONDON -- Tour de France champion Floyd Landis tested positive for high levels of testosterone during the race, his Phonak team said Thursday on its Web site. Phonak said Landis would ask for an analysis of his backup "B" sample "to prove either that this result is coming from a natural process or that this is resulting from a mistake."
The statement came a day after the UCI, cycling's world governing body, said an unidentified rider had failed a drug test during the Tour. The Swiss-based Phonak team said it was notified by the UCI on Wednesday that Landis' sample showed "an unusual level of testosterone/epitestosterone" when he was tested after stage 17 of the race last Thursday. Landis made a remarkable comeback in that Alpine stage, racing far ahead of the field for a solo win that moved him from 11th to third in the overall standings. He regained the leader's yellow jersey two days later. "The team management and the rider were both totally surprised of this physiological result," the Phonak statement said. Phonak said Landis would ask for an analysis of his backup "B" sample "to prove either that this result is coming from a natural process or that this is resulting from a mistake." Landis has been suspended by his team pending the results. If the second sample confirms the initial finding, he will be fired from the team, Phonak said. Landis failed to show up for a one-day race in Denmark on Thursday, a day after missing a scheduled event in the Netherlands. Dutch news agency ANP quoted his teammate Koos Moerenhout as saying that Landis had pain from his hip problem and had gone to see his doctor in Germany. He plans to have hip replacement surgery this fall to ease pain in the arthritic joint still aching from a 2003 crash during a training ride. "We were told by the other two riders that he couldn't join because he was traveling with team manager [John] Lelangue to his doctor in Germany," event organizer Theo van der Westerlaken said. "That's all we know." Landis did take part in a criterium race Tuesday in Stiphout, Netherlands, winning the event. Landis won the Tour de France on Sunday, keeping the title in U.S. hands for the eighth straight year after Lance Armstrong's record seven victories. On the eve of the Tour's start, nine riders -- including pre-race favorites Jan Ullrich and Ivan Basso -- were ousted, implicated in a Spanish doping investigation. The Associated Press and Reuters contributed to this report.

Oh shit. After Stage 17?

That's, well, disturbing.

**Donger** · 07-27-2006, 08:58 AM

Quote:

Originally Posted by Saulbadguy

Lance did it.

**cdcox** · 07-27-2006, 09:02 AM

Quote:

Originally Posted by Donger

Oh shit. After Stage 17?

That's, well, disturbing.

Yep. Especially since Landis never had a day where he was super dominant like that in his past.

07-27-2006, 08:24 AM
The Poz Enjoyer of things Join Date: Jul 2005 Location: Toronto Casino cash: $10012210	Landis gives positive drugs test http://news.bbc.co.uk/sport2/hi/othe...ng/5221122.stm Landis gives positive drugs test Tour de France winner Floyd Landis has given a positive drugs test. The American, who claimed victory in the Tour de France on Sunday, has tested positive for the male sex hormone testosterone. More to follow. It isn't football, but it makes me laugh how stupid some people are.
Posts: 2,178

07-27-2006, 08:36 AM	#2
cdcox www.nfl-forecast.com Join Date: Sep 2000 Casino cash: $2141769	The dopers are ruining cycling. Most of the favorites got thrown out before the race even started for doping.
Posts: 45,544

07-27-2006, 08:40 AM	#3
hawkchief Veteran Join Date: Oct 2005 Casino cash: $2628600	Who was 2nd in the Tour DF? Guess they will become the champ now, eh? After all of the tests Lance Armstrong unerwent for the past 8 years, if this is true, how in the world did Landis expect to get away with this? Just plain stupid.
Posts: 1,878

07-27-2006, 08:44 AM	#4
Mr. Kotter The Dude Abides Join Date: Apr 2001 Location: Dakota Country Casino cash: $5635285	Testosterone, eh? I've always wondered, how do they "test" for doping for something your body produces naturally. I mean, my 'testosterone' levels are off the chart....and I certainly don't "dope." Anyone know? __________________ "I've always said I worry about legacy and winning rings more than making money at this moment...We see what's going on around the league, but at the same time, I'll never do anything that's going to hurt us from keeping the great players around me.”
Posts: 46,365

07-27-2006, 08:46 AM	#5
Donger "Think BOOM!" Join Date: Nov 2003 Location: 33.675° N 106.475° W Casino cash: $9999900 VARSITY	Steroid profiling has become an additional tool in dope control to detect changes in the normal pattern of excreted steroids. These changes may be the result of the misuse of testosterone, a precursor (androstenedione) or an active metabolite of testosterone (dihydrostestosterone) and/or long-term misuse of synthetic anabolic steroids. Testing for testosterone administration has been routinely carried out by analysis of the ratio of testosterone glucuronide to epitestosterone glucuronide, usually known simply as the T/E ratio (Donike M. et al, 1985). Considerations have varied slightly over the years and the present criterion for suspicion of testosterone administration is an abnormally elevated T/E ratio in urine. For some sport bodies the criterion is when the value exceeds the range normally found in humans and thought to be consistent with normal endogenous production. For other bodies, the rule is based on a ratio higher than the usual population (cut-off 6:1) but they accept the obligation to perform additional research in order to exclude the small percentage of people having high T/E ratios due to physiological or pathological conditions (Donike M. et al., 1993; Baezinger J. et al., 1994; Kicman A.T. et al., 1990). Evidence has accumulated in recent years that T/E ratios are relatively stable in a given subject. Work carried out by different authors shows that deviations from a normal baseline value for a given individual should be the starting point for a suspicion of testosterone administration. It has also been shown that there exist, at least, two different classes of "normal" population, one with T/E values around 1-2 and another with T/E values of around 0.2-0.3, the latter mainly concentrated among the Mongoloid race group (Park J. et al., 1990; de la Torre X. et al., 1997). Several authors have studied the effects of testosterone administration on many parameters and they have reached the conclusion that, if suitably chosen, some of these parameters may be highly indicative. Among the more interesting, there is the high increase in the testosterone/17 hydroxy-progesterone (T/17OHP) ratio and in the testosterone/luteinizing hormone (T/LH) ratio. The effects are based on the negative feedback of testosterone, both the release of LH by the hypophysis and the amount of some of its synthetic precursors present in the body, such as 17OHP. Testosterone is usually administered as testosterone enanthate or as one of many other esters. These compounds were supposed to hydrolyse rapidly and completely in the body to release free testosterone. Modern methodology now allows us to determine that small amounts remain in the body for a long time. The finding of such compounds (exogenous: not existing in our body) in the blood would be indicative of testosterone administration (de la Torre X., et al., 199.). It is possible to establish a list of generally accepted scientific facts that should be the basis for a rational approach to the problem of detection and confirmation of cases of testosterone doping. Those premises can be listed as follows: 1. T/E ratio in urine is fairly stable in a given individual 2. External testosterone administration disturbs some selected parameters such as T/17OHP in blood plasma and T/E in urine. The T/LH ratio both in blood plasma and urine is also affected. Many other markers have been studied in both plasma and urine but they have offered less definitive results. 3. The finding of esters of testosterone in blood plasma demonstrates testosterone administration. __________________ I think the young people enjoy it when I "get down," verbally, don't you?
Posts: 181,740

07-27-2006, 08:49 AM	#7
Donger "Think BOOM!" Join Date: Nov 2003 Location: 33.675° N 106.475° W Casino cash: $9999900 VARSITY	I'd imagine that Phonak will ask that his B sample be tested. Either way, this sucks. __________________ I think the young people enjoy it when I "get down," verbally, don't you?
Posts: 181,740

07-27-2006, 08:52 AM	#8
hawkchief Veteran Join Date: Oct 2005 Casino cash: $2628600	Way to embarrass your country, Landass!
Posts: 1,878

07-27-2006, 08:55 AM	#11
Saulbadguy When a nightmare becomes real Join Date: Nov 2003 Casino cash: $2276966	Big deal. Lance did it. This guy did it. Noone really cares about cycling.
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07-27-2006, 08:56 AM	#12
DiaperBoy27 Starter Join Date: Jul 2006 Location: Grandma's House Casino cash: $9996952	is the source french?
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