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10-25-2015, 04:27 PM | #181 |
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Just like oil and energy companies, instead of fighting just jump on board and making money from it. Both pharma and energy companies have the infrastructure to dominate the markets if they would just stop being dicks and move forward.
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10-25-2015, 04:30 PM | #182 | |
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EDIT: I should mention it was ingested orally |
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10-25-2015, 04:38 PM | #183 | |
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http://www.ncbi.nlm.nih.gov/pubmed/20053780
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10-25-2015, 04:39 PM | #184 | |
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We could talk about anecdotal evidence vs. actual trials, colon and GBM being completely different tumors made up of completely different tissue and governed by completely different mediators of tumor cell growth, dosages, delivery to the colon (delivered directly to the colon by ingestion) vs. the brain (must be taken up into the bloodstream, metabolized by the liver, traverse the Blood-brain barrier, and delivered to the site of the tumor in high enough concentrations) etc etc, but I don't think we will agree.
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10-25-2015, 04:41 PM | #185 |
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What about the energy companies? What should they move forward with, burning pot to produce energy?
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10-25-2015, 04:41 PM | #186 | |
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Oh I don't doubt there are complications - but the body has natural CBD receptors in the brain - so to get that chemical to the brain is not as much of a stretch (and it's non-psychoactive) - check out the link I posted in my last post |
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10-25-2015, 04:42 PM | #187 | |
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10-25-2015, 04:44 PM | #188 |
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When my brother was up at Mayo in 2012/2013 they asked his oncologist about CBD, weed etc as treatment for his stage 4 GBM.
The doc said it was showing to kill the tumor, but the only way it'd been tested was direct injection into the tumor. Which led to the two problems with that. One, not every tumor can be reached, and two, nobody was making the stuff in a way a doctor would ever approve as clean enough to inject directly into someone's brain. Weed and the polio virus currently look like the best hopes, which is great! |
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10-25-2015, 04:44 PM | #189 |
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I'm not talking about complications. I'm talking about sufficient concentrations after ingesting the oil, it being metabolized, and it traversing an anatomic barrier in the brain that filters substances. That is much more complicated than simply ingesting something and having a portion of it mechanically delivered unchanged to your colon.
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10-25-2015, 04:45 PM | #190 | |
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0.5 mg per mouse is a high dose? It's also a non-psychoactive ingredient, so there is room to really amp up the dose without much if any negative side effects |
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10-25-2015, 04:46 PM | #191 | |
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10-25-2015, 04:47 PM | #192 | |
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I'm not attacking you - we are having a discussion - you obviously know more than I do about the chemical properties - I'm just trying to traverse the landscape as a lay person with a little bit of anecdotal evidence |
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10-25-2015, 04:50 PM | #193 |
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Yes, it is. 0.5 mg in a 20 gram mouse translates to 25 mg/kg in the mouse. 25 mg/kg in a 160 pound man is 1750 mg per dose.
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10-25-2015, 04:53 PM | #194 | |
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Complications=side effects I was using complicated the second time to state that the mode of delivery is complex.
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10-25-2015, 04:56 PM | #195 |
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I'm sorry if I personally attacked you, Denver. That was not my intention. I got a little worked up.
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