What direction? If its just speculation on your part, its not a spoiler.
I'll hide it anyway. And to be honest I haven't read up on the show anywhere online so there may be others out there with similar conclusions...
Spoiler!
If you watch the trailers/previews you'll notice that they have a quick effect on the "R" in the title. It briefly, for a frame or two, flips to resemble a Russian "R".
Also, in the first episode he goes to a Moscau (sp?) cafe.
So I think you're going to find that one reality is one where the Soviets/communists "won" and the other will be our current reality where communism and the Soviet Union died.
The twist will be that the main Howard character we followed in the first episode -- the one who is visiting the hospital each night -- is actually the Soviet Howard.