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#34876 | |
"Think BOOM!"
Join Date: Nov 2003
Location: 33.675° N 106.475° W
Casino cash: $6829900
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Quote:
He would go on to say that the state's rural communities are also seeing large outbreaks. Officials continue to point to the positivity rate, the percentage of positive tests among the number of people tested, as a sign the state is still trending in the right direction, with the rate currently sitting at 5.3 percent, according to the state's COVID-19 dashboard.
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I think the young people enjoy it when I "get down," verbally, don't you? |
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Posts: 191,134
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#34877 |
Court Jester
Join Date: Aug 2000
Location: Orlando
Casino cash: $-717600
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I’ll go back as soon as they open, although I have no idea what’s out now. I’ve already flown the last 3 weekends on completely full flights, so a half empty movie theatre will be a piece of cake.
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Posts: 20,689
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#34878 |
Now you've pissed me off!
Join Date: Jan 2006
Casino cash: $7199572
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You're also vaccinating against four different strains of disease with a high degree of antigenic shift. It's a lot different from what we've seen with this virus so far.
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"When the Know-Nothings get control, it will read 'all men are created equal, except negroes, and foreigners, and Catholics.' When it comes to this I should prefer emigrating to some country where they make no pretense of loving liberty – to Russia, for instance, where despotism can be taken pure, and without the base alloy of hypocrisy.”--Abraham Lincoln |
Posts: 75,078
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#34879 |
"Think BOOM!"
Join Date: Nov 2003
Location: 33.675° N 106.475° W
Casino cash: $6829900
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Reposting this, since it seems to be pertinent:
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I think the young people enjoy it when I "get down," verbally, don't you? |
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#34880 |
"Think BOOM!"
Join Date: Nov 2003
Location: 33.675° N 106.475° W
Casino cash: $6829900
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I think the young people enjoy it when I "get down," verbally, don't you? |
Posts: 191,134
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#34881 |
Time Keeps On Slipping
Join Date: Sep 2004
Location: Overland Park
Casino cash: $3579900
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So THAT'S where I picked up the SARS 2 moniker...
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"Turn the channel to 26!" |
Posts: 27,417
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#34882 | |
Supporter
Join Date: Feb 2005
Location: Olathe, Ks
Casino cash: $-995873
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That being said even with a vaccine I don't think Covid is going to go away. It will be around for probably longer than any of us are going to live anyway. |
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Posts: 132,428
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#34883 | |
Kind of a mod
Join Date: Aug 2005
Location: Donkey Land
Casino cash: $-1773101
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Posts: 53,146
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#34884 |
Supporter
Join Date: Feb 2005
Location: Olathe, Ks
Casino cash: $-995873
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Possibly. But then so could other effective treatments for that matter.
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Posts: 132,428
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#34885 | |
Now you've pissed me off!
Join Date: Jan 2006
Casino cash: $7199572
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Quote:
There are different strains of SARS-CoV-2, but different strains don't always mean you need different treatments. That depends on the difference from one virus to another. There is evidence that this particular disease does not mutate that much, which means that an effective treatment is likely to confer much broader protection than other viruses. This is also the rationale behind mass vaccination campaigns in general--if everyone is vaccinated for the measles and it can't establish a reservoir it can't mutate; if people don't get vaccinated the disease has an opportunity to mutate, which would then render the vaccine less effective. In the case of the flu, there are almost 200 different subtypes and 131 types that have been found in people, but what you are commonly vaccinated against are H1N1, H3N2 (both flu A types) and two types of flu B. Within those viruses, there is enough genetic differentiation to make the vaccine a moving target--they try to zero in on the unique characteristics of the viruses of that year. The ability of flu to mutate rapidly is why treatments like amantadine is now functionally worthless (and why Tamiflu soon will be, too). HIV is even more prone to mutation than the flu, but I don't like the analogy of it being a genius--it mutates so readily because its proofreading enzymes are really inaccurate. Nevertheless, that's why you need combination therapy to keep it in check; as it mutates so rapidly, the odds of resistance become virtually certain if on a single therapy. There are numerous different groups of HIV-1 (M, N, O, P) and within those groups there are subtypes, and within those subtypes there are numerous strains, and those strains can develop resistance to therapies over time, and sometimes clinicians even use that to their advantage. One of the reasons why many people starting out on anti-HIV therapy begin with a regimen with emtricitabine is because the mutation that confers resistance to it (M184, IIRC) actually make the virus less "fit". What is the point of all this? Viruses that are more likely to mutate are harder to treat because your initial therapies are less likely to work as the genetic code of the virus changes over time. Given that SARS-CoV-2 has shown little mutation to this point, the odds of a vaccine conferring superior protection in comparison to a flu vaccine are likely if we can find one that stimulates an adequate immune response.
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"When the Know-Nothings get control, it will read 'all men are created equal, except negroes, and foreigners, and Catholics.' When it comes to this I should prefer emigrating to some country where they make no pretense of loving liberty – to Russia, for instance, where despotism can be taken pure, and without the base alloy of hypocrisy.”--Abraham Lincoln |
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Posts: 75,078
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#34886 |
In Search of a Life
Join Date: Oct 2010
Casino cash: $-1530347
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Why do you always have to play some contrarian dumb shit? A vaccine would "possibly" get us back to normal faster? Things won't go back to normal until a vast majority of people aren't scared and a lot of people aren't going to lose their fear just because there are some ways to treat COVID19. A large number of people say they aren't going back to their previous lifestyle until there is a vaccine.
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Posts: 20,459
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#34887 | |
In Search of a Life
Join Date: Oct 2010
Casino cash: $-1530347
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Posts: 20,459
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#34888 | |
Beyond the Rapids
Join Date: May 2003
Location: Langley, VA
Casino cash: $-370000
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Posts: 80,659
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#34889 | |
Just Lurking
Join Date: Feb 2009
Location: Ozark Mountain Country
Casino cash: $-1862096
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Posts: 2,121
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#34890 | |
Kind of a mod
Join Date: Aug 2005
Location: Donkey Land
Casino cash: $-1773101
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Quote:
If I've been vaccinated and I go to the store and come across an 80-year-old not wearing a mask who hasn't, that's their choice. Right now, someone like that doesn't have much of a choice but to hide or take their chances. |
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Posts: 53,146
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