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#57226 |
Generational Player
Join Date: May 2017
Location: Honolulu
Casino cash: $440400
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Effectiveness of Covid-19 Vaccination Against Risk of Symptomatic Infection, Hospitalization, and Death Up to 9 Months: A Swedish Total-Population Cohort Study
34 Pages Posted: 25 Oct 2021 Peter Nordström University of Umea - Unit of Geriatric Medicine Marcel Ballin University of Umea Anna Nordström University of Umea Findings: Vaccine effectiveness of BNT162b2 against infection waned progressively from 92% (95% CI, 92-93, P<0·001) at day 15-30 to 47% (95% CI, 39-55, P<0·001) at day 121-180, and from day 211 and onwards no effectiveness could be detected https://papers.ssrn.com/sol3/papers....act_id=3949410 |
Posts: 10,024
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#57227 |
Seize life. Be an ermine.
Join Date: Jul 2001
Location: My house
Casino cash: $-572449
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Russia.
Vaccine skepticism must be the greatest non-war Victory one country has ever had over another.
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Active fan of the greatest team in NFL history. |
Posts: 145,366
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#57228 |
Kind of a mod
Join Date: Aug 2005
Location: Donkey Land
Casino cash: $-1773101
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I certainly wonder sometimes. My work is starting up a digital literacy course, and one of the topics is identifying misinformation. I almost think it should be a required course for the entire population.
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Posts: 53,146
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#57229 | ||
Banded
Join Date: Feb 2001
Location: Oz
Casino cash: $-579308
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How does the pulse ox measure? According to this PC Mag review:
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Conversation would be vastly improved by the constant use of four simple words: I do not know. |
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Posts: 42,471
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#57230 | |
I love your mom
Join Date: Feb 2020
Location: Sturgeon Falls, Ontario
Casino cash: $-935043
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Posts: 7,778
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#57231 | |
Generational Player
Join Date: May 2017
Location: Honolulu
Casino cash: $440400
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Posts: 10,024
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#57232 | |
Veteran
Join Date: May 2010
Casino cash: $2855985
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The difference in transmission was less than 10%. So transmission from a vaccinated individual to vaccinated individual was less than 10% lower than the transmission from unvaccinated to unvaccinated. Which any decrease in transmission is always good. However, let's look at it from the other side of the argument. Being vaccinated also means you are more likely to have mild or no symptoms if infected. So one could argue that you are more likely to be in close contact with other people while infected. Get vaccinated or not it's your choice. But the whole I am a good person and doing this to save Grandma thing is bullshit. |
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Posts: 2,005
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#57233 | |
Banded
Join Date: Feb 2001
Location: Oz
Casino cash: $-579308
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That being said and like you mentioned, as far as I'm concerned, getting the vaccine is the wise choice because it is proven to reduce the severity.
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Conversation would be vastly improved by the constant use of four simple words: I do not know. |
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#57234 | |
In Search of a Life
Join Date: Jul 2009
Casino cash: $-625936
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Posts: 84,191
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#57235 |
Supporter
Join Date: Mar 2003
Casino cash: $767626
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He won't. He is a complete tool that thinks he is a researcher because he sees videos on youtube and memes on twitter/facebook.
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Posts: 17,241
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#57236 | |
MVP
Join Date: May 2001
Location: midtown KC
Casino cash: $-1265090
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I'm getting pretty frustrated with trying to protect people who won't do the bare minimum to protect themselves and/or their families, friends, and neighbors. |
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Posts: 19,444
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#57237 | |
MVP
Join Date: May 2001
Location: midtown KC
Casino cash: $-1265090
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I just got my Pfizer booster yesterday. My arm is sore, no other side affects. |
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Posts: 19,444
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#57238 |
"Think BOOM!"
Join Date: Nov 2003
Location: 33.675° N 106.475° W
Casino cash: $6829900
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Here's the information from Pfizer. Not sure what titters have to do with it:
https://www.pfizer.com/news/press-re...micron-variant Wednesday, December 08, 2021 - 06:54am
NEW YORK & MAINZ, Germany--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced results from an initial laboratory study demonstrating that serum antibodies induced by the Pfizer-BioNTech COVID-19 Vaccine (BNT162b2) neutralize the SARS-CoV-2 Omicron variant after three doses. Sera obtained from vaccinees one month after receiving the booster vaccination (third dose of BNT162b2 vaccine) neutralized the Omicron variant to levels that are comparable to thoseobserved for the wild-type SARS-CoV-2 spike protein after two doses. This press release features multimedia. View the full release here: https://www.businesswire.com/news/ho...1208005542/en/ Sera from individuals who received two doses of the current COVID-19 vaccine did exhibit, on average, more than a 25-fold reduction in neutralization titers against the Omicron variant compared to wild-type, indicating that two doses of BNT162b2 may not be sufficient to protect against infection with the Omicron variant. However, as the vast majority of epitopes targeted by vaccine-induced T cells are not affected by the mutations in Omicron, the companies believe that vaccinated individuals may still be protected against severe forms of the disease and are closely monitoring real world effectiveness against Omicron, globally. A more robust protection may be achieved by a third dose as data from additional studies of the companies indicate that a booster with the current COVID-19 vaccine from Pfizer and BioNTech increases the antibody titers by 25-fold. According to the companies’ preliminary data, a third dose provides a similar level of neutralizing antibodies to Omicron as is observed after two doses against wild-type and other variants that emerged before Omicron. These antibody levels are associated with high efficacy against both the wild-type virus and these variants. A third dose also strongly increases CD8+ T cell levels against multiple spike protein epitopes which are considered to correlate with the protection against severe disease. Compared to the wild-type virus, the vast majority of these epitopes remain unchanged in the Omicron spike variant. “Although two doses of the vaccine may still offer protection against severe disease caused by the Omicron strain, it’s clear from these preliminary data that protection is improved with a third dose of our vaccine,” said Albert Bourla, Chairman and Chief Executive Officer, Pfizer. “Ensuring as many people as possible are fully vaccinated with the first two dose series and a booster remains the best course of action to prevent the spread of COVID-19.” “Our preliminary, first dataset indicate that a third dose could still offer a sufficient level of protection from disease of any severity caused by the Omicron variant,” said Ugur Sahin, M.D., CEO and Co-Founder of BioNTech. “Broad vaccination and booster campaigns around the world could help us to better protect people everywhere and to get through the winter season. We continue to work on an adapted vaccine which, we believe, will help to induce a high level of protection against Omicron-induced COVID-19 disease as well as a prolonged protection compared to the current vaccine.” While these results are preliminary, the companies will continue to collect more laboratory data and evaluate real-world effectiveness to assess and confirm protection against Omicron and inform the most effective path forward. On November 25, the companies started to develop an Omicron-specific COVID-19 vaccine. The development will continue as planned in the event that a vaccine adaption is needed to increase the level and duration of protection against Omicron. First batches of the Omicron-based vaccine can be produced and are planned to be ready for deliveries within 100 days, pending regulatory approval. Pfizer and BioNTech have tested other variant-specific vaccines as well, which have produced very strong neutralization titers and a tolerable safety profile. Based on this experience the companies have high confidence that if needed they can deliver an Omicron-based vaccine in March 2022. The companies have also previously initiated clinical trials with variant-specific vaccines (Alpha, Beta, Delta & Alpha/Delta Mix) and data from these studies will be submitted to regulatory agencies around the world to help accelerate the process of adapting the vaccine and gaining regulatory authorization or approval of an Omicron-specific vaccine, if needed. The companies have previously announced that they expect to produce four billion doses of BNT162b2 in 2022, and this capacity is not expected to change if an adapted vaccine is required.
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I think the young people enjoy it when I "get down," verbally, don't you? |
Posts: 191,117
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#57239 | |
MVP
Join Date: May 2001
Location: midtown KC
Casino cash: $-1265090
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Most people's arguments for NOT getting the vaccine are either that they don't think they're at risk for serious illness, or they just think this is all overblown. A lot of people are dead that didn't need to be. A lot of people have long term problems now from having Covid that they didn't have to have. If everybody that could would just get vaccinated, then this is the flu. Until then, people at risk and stubborn people will keep dying. a lot of people THINK they're a lot healthier than they are. A lot of people have underlying issues that they're completely unaware of. Just get the damned shots. It's only partly about you. If you don't care about yourself, fine, then do it for ****ing grandma. One of our own just had a ****ing stroke at what, 50!? Y'all eat ****ing McRibs! Argue the finer points of Whataburger vs. whatever other horrible for you fast food restaurants...you're probably not as healthy as you think you are. The shots are free. It's insurance. I don't understand why this is a political argument. |
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Posts: 19,444
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#57240 | |
Sometimes it's black and white
Join Date: Nov 2004
Location: California
Casino cash: $1284900
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Sometimes. |
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Posts: 6,758
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