***NON-POLITICAL COVID-19 Discussion Thread***

[JakeF]

A couple of reminders...

Originally Posted by Bwana

Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.

Originally Posted by Dartgod

People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Apparently the CoronaVirus can survive on a inanimate objects, such as door knobs, for 9 days.

California coronavirus case could be first spread within U.S. community, CDC says
By SOUMYA KARLAMANGLA, JACLYN COSGROVE
FEB. 26, 2020 8:04 PM

The Centers for Disease Control and Prevention is investigating what could be the first case of novel coronavirus in the United States involving a patient in California who neither recently traveled out of the country nor was in contact with someone who did.

“At this time, the patient’s exposure is unknown. It’s possible this could be an instance of community spread of COVID-19, which would be the first time this has happened in the United States,” the CDC said in a statement. “Community spread means spread of an illness for which the source of infection is unknown. It’s also possible, however, that the patient may have been exposed to a returned traveler who was infected.”

The individual is a resident of Solano County and is receiving medical care in Sacramento County, according to the state Department of Public Health.

The CDC said the “case was detected through the U.S. public health system — picked up by astute clinicians.”

Officials at UC Davis Medical Center expanded on what the federal agency might have meant by that in an email sent Wednesday, as reported by the Davis Enterprise newspaper.

The patient arrived at UC Davis Medical Center from another hospital Feb. 19 and “had already been intubated, was on a ventilator, and given droplet protection orders because of an undiagnosed and suspected viral condition,” according to an email sent by UC Davis officials that was obtained by the Davis Enterprise.

The staff at UC Davis requested COVID-19 testing by the CDC, but because the patient didn’t fit the CDC’s existing criteria for the virus, a test wasn’t immediately administered, according to the email. The CDC then ordered the test Sunday, and results were announced Wednesday. Hospital administrators reportedly said in the email that despite these issues, there has been minimal exposure at the hospital because of safety protocols they have in place.

A UC Davis Health spokesperson declined Wednesday evening to share the email with The Times.

Since Feb. 2, more than 8,400 returning travelers from China have entered California, according to the state health department. They have been advised to self-quarantine for 14 days and limit interactions with others as much as possible, officials said.

“This is a new virus, and while we are still learning about it, there is a lot we already know,” Dr. Sonia Angell, director of the California Department of Public Health, said in a statement. “We have been anticipating the potential for such a case in the U.S., and given our close familial, social and business relationships with China, it is not unexpected that the first case in the U.S. would be in California.”

It is not clear how the person became infected, but public health workers could not identify any contacts with people who had traveled to China or other areas where the virus is widespread. That raises concern that the virus is spreading in the United States, creating a challenge for public health officials, experts say.

“It’s the first signal that we could be having silent transmission in the community,” said Lawrence Gostin, director of the World Health Organization Collaborating Center on National and Global Health Law. “It probably means there are many more cases out there, and it probably means this individual has infected others, and now it’s a race to try to find out who that person has infected.”

On Tuesday, the CDC offered its most serious warning to date that the United States should expect and prepare for the coronavirus to become a more widespread health issue.

“Ultimately, we expect we will see coronavirus spread in this country,” said Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases. “It’s not so much a question of if, but a question of when.”

According to the CDC’s latest count Wednesday morning, 59 U.S. residents have tested positive for the new strain of coronavirus — 42 of whom are repatriated citizens from a Diamond Princess cruise. That number has grown by two since Messonnier’s last count Tuesday, although the CDC was not immediately available to offer details on the additional cases.

More than 82,000 cases of coronavirus have been reported globally, and more than 2,700 people have died, with the majority in mainland China, the epicenter of the outbreak.

But public health leaders have repeatedly reminded residents that the health risk from the novel coronavirus to the general public remains low.

“While COVID-19 has a high transmission rate, it has a low mortality rate,” the state Department of Public Health said in a statement Wednesday. “From the international data we have, of those who have tested positive for COVID-19, approximately 80% do not exhibit symptoms that would require hospitalization. There have been no confirmed deaths related to COVID-19 in the United States to date.”

CDC officials have also warned that although the virus is likely to spread in U.S. communities, the flu still poses a greater risk.

Gostin said the news of potential silent transmission does not eliminate the possibility of containing the virus in the U.S. and preventing an outbreak.

“There are few enough cases that we should at least try,” he said. “Most of us are not optimistic that that will be successful, but we’re still in the position to try.”

[dirk digler]

Originally Posted by petegz28

Oh yeah they did. Gilead claimed they were wrong. FWIW I don't believe jack shit from the WHO right now.

This trial was run by U.S.’s National Institute of Allergy and Infectious Diseases not Gilead. I did read China tried to steal the patent of Remdesivir

[Bwana]

Originally Posted by dirk digler

This trial was run by U.S.’s National Institute of Allergy and Infectious Diseases not Gilead. I did read China tried to steal the patent of Remdesivir

Of course they did, slippery little douche bags.

[Monticore]

Originally Posted by IowaHawkeyeChief

Vitamin D is also one of the few nutrients we produce by exposure to the Sun. We should probably be getting out of our houses at some point.

Nobody is saying you can't go outside, I spent all weekend outside, also mushrooms are a source of vitamin D if exposed to UV light.

[IowaHawkeyeChief]

Originally Posted by Monticore

Nobody is saying you can't go outside, I spent all weekend outside, also mushrooms are a source of vitamin D if exposed to UV light.

Many states won't let you on a boat on a lake by yourself and their parks and walking trails are closed...

[O.city]

Originally Posted by dirk digler

Huge ****ing news

Gilead announces results from Phase 3 trial of investigational antiviral in patients with severe COVID-19: https://t.co/lZFC5Yee8T. pic.twitter.com/oDyYCI7JDX

— Gilead Sciences (@GileadSciences) April 29, 2020

Thats awesome.

Hamas i think said it a while back, but similar to Tamiflu, it's all about the timing in antivirals.

[Monticore]

Originally Posted by IowaHawkeyeChief

Many states won't let you on a boat on a lake by yourself and their parks and walking trails are closed...

Seems a bit extreme to me, one advantage of living up north I guess finding outside space is pretty easy.

[limested]

Originally Posted by dirk digler

Huge ****ing news

Gilead announces results from Phase 3 trial of investigational antiviral in patients with severe COVID-19: https://t.co/lZFC5Yee8T. pic.twitter.com/oDyYCI7JDX

— Gilead Sciences (@GileadSciences) April 29, 2020

So the company that makes the drug that is trying to prop up its stock price says it works. imagine that.

[dirk digler]

Originally Posted by limested

So the company that makes the drug that is trying to prop up its stock price says it works. imagine that.

The trial was run by U.S.’s National Institute of Allergy and Infectious Diseases not Gilead

[IowaHawkeyeChief]

Originally Posted by Monticore

Seems a bit extreme to me, one advantage of living up north I guess finding outside space is pretty easy.

no doubt

['Hamas' Jenkins]

"A second SIMPLE trial is evaluating the safety and efficacy of 5-day and 10-day dosing durations of remdesivir administered intravenously in patients with moderate manifestations of COVID-19, compared with standard of care. The results from the first 600 patients of this study are expected at the end of May."

That will be where the rubber really meets the road. Without a comparison to standard of care it's difficult to ascertain how much improvement was due to the drug vs. the normal course of the illness. Hopefully that sample size is large enough to meet power.

With that said, if you look pooled data from what we do have, that would be a relative risk reduction of hospitalization at Day 14 of 25%, an absolute risk reduction of 13%, and a number needed to treat of 7.7.

Translation: For every 8 people that they treat with Remdesivir, one will get out of the hospital by day 14 that wouldn't have before.

[SAUTO]

Originally Posted by IowaHawkeyeChief

Many states won't let you on a boat on a lake by yourself and their parks and walking trails are closed...

what states are those?

[O.city]

Originally Posted by 'Hamas' Jenkins

"A second SIMPLE trial is evaluating the safety and efficacy of 5-day and 10-day dosing durations of remdesivir administered intravenously in patients with moderate manifestations of COVID-19, compared with standard of care. The results from the first 600 patients of this study are expected at the end of May."

That will be where the rubber really meets the road. Without a comparison to standard of care it's difficult to ascertain how much improvement was due to the drug vs. the normal course of the illness. Hopefully that sample size is large enough to meet power.

With that said, if you look pooled data from what we do have, that would be a relative risk reduction of hospitalization at Day 14 of 25%, an absolute risk reduction of 13%, and a number needed to treat of 7.7.

Translation: For every 8 people that they treat with Remdesivir, one will get out of the hospital by day 14 that wouldn't have before.

I think this one will end up being better used for mild cases to prevent from getting to that point. The antibody treatment would seem to be better suited for severe casess.

[Indian Chief]

Originally Posted by SAUTO

what states are those?

NJ for one, although they have since walked back the boating ban (still can't rent a boat, has to be one you own)

[IowaHawkeyeChief]

Originally Posted by SAUTO

what states are those?

Michigan for one, probably the strictest. I don't think beaches are open in Southern Florida, NJ and other places. Washington State had closed their hiking trails.

[O.city]

Well, the good news is that while the death rate in NY hit close to projections, the number of hospitalizations have been way below.