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Old 10-23-2007, 06:19 PM  
jAZ jAZ is offline
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Researchers Cure AIDS... not a joke.

If I understand this correctly, they've basically cured AIDS by allowing HIV positive people to have full immune systems.

http://www.sciencedaily.com/releases...1020103343.htm

Researchers Knock Out HIV

ScienceDaily (Oct. 21, 2007) — With the latest advances in treatment, doctors have discovered that they can successfully neutralise the human immunodeficiency virus (HIV). The so-called ‘combination therapy’ prevents HIV from mutating and spreading, allowing patients to rebuild their immune system to the same levels as the rest of the population.

To date, it represents the most significant treatment for patients suffering from HIV.

Professor Jens Lundgren from the University of Copenhagen, together with other members of the research group EuroSIDA, have conducted a study, which demonstrates that the immune system of all HIV-infected patients can be restored and normalised. The only stipulation is that patients begin and continue to follow their course of treatment.

HIV attacks the body’s ability to counteract viruses

Viruses are small organisms that have no independent metabolism. Consequently, when they enter the body they attack living cells and adopt their metabolism. The influenza virus occupies cells in the nose, throat and lungs; the mumps attaches itself to the salivary glands of the ear; while the Polio virus plays on the intestinal tract, blood and salivary glands. In all these instances, our immune system attacks and eliminates the invading virus.

HIV is so deadly because the virus attaches itself to a crucial part of the immune system itself: to the so-called CD4+T lymphocytes, which are white blood corpuscles that help the immune system to fight infections. The Hi-virus forms and invades new CD4+T-lymphocytes. Slowly but surely, the number of healthy CD4+T lymphocytes in the blood fall, while HIV relentlessly weakens the body’s ability to defend itself from infection. Finally, the immune system erodes to such an extent that the infected patient is diagnosed with AIDS. The Hi-virus mutates constantly as it forms and this is why, scientists face a constant battle to find a cure or a vaccine.

Combination therapy knocks out HIV

Combination therapy prevents the virus from forming and mutating in human beings. When the virus is halted in its progress, the number of healthy CD4+T cells begins to rise and patients, who would otherwise die from HIV, can now survive. The immune system is rejuvenated and is apparently able to normalise itself, providing that the combination therapy is maintained. The moment the immune system begins to improve, the HIV-infected patient can no longer be said to be suffering from an HIV infection or disease, already declining in strength.

Findings from the study are published in the medical journal The Lancet - Vol. 370, Issue 9585, 4 August 2007, Pages 407-413

Adapted from materials provided by University Of Copenhagen.
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Old 10-23-2007, 06:46 PM   #16
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Quote:
Originally Posted by bishop_74
Not really a cure since you can't cure viruses. I would agree it is a treatment.
HIV is the virus. It's not a cure for HIV. It's a cure for the condition of AIDS, which used to be a certain outcome of contracting HIV.
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Old 10-23-2007, 06:46 PM   #17
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Old 10-23-2007, 06:51 PM   #18
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Quote:
Originally Posted by FAX
Actually, if true, this could be a very important step forward in the treatment of any number of auto-immune disorders.

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MS?
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Old 10-23-2007, 06:55 PM   #19
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So... are you saying that the old Chris Rock joke is actually going to come true?
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Old 10-23-2007, 06:55 PM   #20
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The journal article came out 2-1/2 months ago. If this was as big a deal as presented in the science daily link, it would have gotten more play in the popular press. It could play out to be worthwhile, but I think it's too early to declare victory.
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Old 10-23-2007, 07:02 PM   #21
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Quote:
Originally Posted by LOCOChief
MS?
That's one, Mr. LOCOChief. There are quite a number of them.

Obviously, because this subject has little to do with the potentially harmful environmental impact of free range chicken poop, it's an area in which I have little or no knowledge. However, a lot of researchers specializing in auto-immune disorders believe that they are caused by the effect certain micro-organisms have on the white blood cells. Basically, the immune system is "tricked" into believing that "good" cells are "bad" and the immune system goes haywire and starts running around killing off the "good" stuff.

If, in fact, they are able to isolate HIV as or before it affects the white blood cells, it sounds as though this approach could hold some promise by also isolating the other micro-organisms which, in the case of auto-immune, are confusing the immune system. It's a thought, anyhow.

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Old 10-23-2007, 07:05 PM   #22
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Good, now they need to get started on that bastard cancer.
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Old 10-23-2007, 07:12 PM   #23
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Quote:
Originally Posted by FAX
However, a lot of researchers specializing in auto-immune disorders believe that they are caused by the effect certain micro-organisms have on the white blood cells. Basically, the immune system is "tricked" into believing that "good" cells are "bad" and the immune system goes haywire and starts running around killing off the "good" stuff.
Pretty close. The disease I have, chronic lymphocitic thyroiditis, aka Hashimoto's encephalopathy, is caused by my thyroid malfunctioning and causing my immune system to attack my brain. It damn near did me in about 1 1/2 years ago. It's a rare desease so it took a while for it to be diagnosed, meanwhile I was a babbling idiot in the hospital attacking everything that moved (did I mention it made me a tad aggressive?), once the figured out what the problem was I got steroid therapy which suppressed my immune system and allows me to function pretty much normally. I do have occasional relapses and I'm very succeptable to colds, rashes, and pretty much anything else.
I think MS is treated in pretty much the same manner. When I have a relapse I usually get steroid infusions alongside MS patients getting the same thing (solumedrol).
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Old 10-23-2007, 07:17 PM   #24
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Great news!! Pass the needle!!

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not funny. especially if you've known someone die like that.
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Old 10-23-2007, 07:20 PM   #25
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Originally Posted by alnorth
So... are you saying that the old Chris Rock joke is actually going to come true?
It will be, if they create a vaccine. Is this the logical path of this 'cure'?

I also hear the immortal words of Dennis Miller: "Imagine the day they cure AIDS. If you can't get laid on that day, give it up."

GoChiefs, pay attention.
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Old 10-23-2007, 07:21 PM   #26
pr_capone pr_capone is offline
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Quote:
Originally Posted by QuikSsurfer
not funny. especially if you've known someone die like that.
By AIDS or by sticking themselves with needles?
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Old 10-23-2007, 07:21 PM   #27
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Quote:
Originally Posted by JohninGpt
Pretty close. The disease I have, chronic lymphocitic thyroiditis, aka Hashimoto's encephalopathy, is caused by my thyroid malfunctioning and causing my immune system to attack my brain. It damn near did me in about 1 1/2 years ago. It's a rare desease so it took a while for it to be diagnosed, meanwhile I was a babbling idiot in the hospital attacking everything that moved (did I mention it made me a tad aggressive?), once the figured out what the problem was I got steroid therapy which suppressed my immune system and allows me to function pretty much normally. I do have occasional relapses and I'm very succeptable to colds, rashes, and pretty much anything else.
I think MS is treated in pretty much the same manner. When I have a relapse I usually get steroid infusions alongside MS patients getting the same thing (solumedrol).
Man, oh man. I'm very sorry to hear about this, Mr. JohninGpt. Very sorry, indeed.

The treatment makes sense given what they know about auto-immune, though. They're shutting down the immune system which is reacting incorrectly to some influence. It would be wonderful if they could turn that around, identify the cause that is affecting the immune system, and address that instead. There's always hope, though, and advances like this might open the door to a true cure.

Meanwhile, here's to your health, my friend.

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Old 10-23-2007, 07:22 PM   #28
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ok now that we have been diverted for 20+ years.
can we get back to Cancer, MS, autism, etc.
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Old 10-23-2007, 07:23 PM   #29
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Quote:
Originally Posted by QuikSsurfer
not funny. especially if you've known someone die like that.
Sometimes, I post without thinking first. I need to work on that.

But honestly, Mr. QuikSsurfer, I have mixed feelings about a person who uses a dirty needle.

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Old 10-23-2007, 07:24 PM   #30
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Quote:
Originally Posted by pr_capone
By AIDS or by sticking themselves with needles?
both.
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