***NON-POLITICAL COVID-19 Discussion Thread***

[JakeF]

A couple of reminders...

Originally Posted by Bwana

Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.

Originally Posted by Dartgod

People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Apparently the CoronaVirus can survive on a inanimate objects, such as door knobs, for 9 days.

California coronavirus case could be first spread within U.S. community, CDC says
By SOUMYA KARLAMANGLA, JACLYN COSGROVE
FEB. 26, 2020 8:04 PM

The Centers for Disease Control and Prevention is investigating what could be the first case of novel coronavirus in the United States involving a patient in California who neither recently traveled out of the country nor was in contact with someone who did.

“At this time, the patient’s exposure is unknown. It’s possible this could be an instance of community spread of COVID-19, which would be the first time this has happened in the United States,” the CDC said in a statement. “Community spread means spread of an illness for which the source of infection is unknown. It’s also possible, however, that the patient may have been exposed to a returned traveler who was infected.”

The individual is a resident of Solano County and is receiving medical care in Sacramento County, according to the state Department of Public Health.

The CDC said the “case was detected through the U.S. public health system — picked up by astute clinicians.”

Officials at UC Davis Medical Center expanded on what the federal agency might have meant by that in an email sent Wednesday, as reported by the Davis Enterprise newspaper.

The patient arrived at UC Davis Medical Center from another hospital Feb. 19 and “had already been intubated, was on a ventilator, and given droplet protection orders because of an undiagnosed and suspected viral condition,” according to an email sent by UC Davis officials that was obtained by the Davis Enterprise.

The staff at UC Davis requested COVID-19 testing by the CDC, but because the patient didn’t fit the CDC’s existing criteria for the virus, a test wasn’t immediately administered, according to the email. The CDC then ordered the test Sunday, and results were announced Wednesday. Hospital administrators reportedly said in the email that despite these issues, there has been minimal exposure at the hospital because of safety protocols they have in place.

A UC Davis Health spokesperson declined Wednesday evening to share the email with The Times.

Since Feb. 2, more than 8,400 returning travelers from China have entered California, according to the state health department. They have been advised to self-quarantine for 14 days and limit interactions with others as much as possible, officials said.

“This is a new virus, and while we are still learning about it, there is a lot we already know,” Dr. Sonia Angell, director of the California Department of Public Health, said in a statement. “We have been anticipating the potential for such a case in the U.S., and given our close familial, social and business relationships with China, it is not unexpected that the first case in the U.S. would be in California.”

It is not clear how the person became infected, but public health workers could not identify any contacts with people who had traveled to China or other areas where the virus is widespread. That raises concern that the virus is spreading in the United States, creating a challenge for public health officials, experts say.

“It’s the first signal that we could be having silent transmission in the community,” said Lawrence Gostin, director of the World Health Organization Collaborating Center on National and Global Health Law. “It probably means there are many more cases out there, and it probably means this individual has infected others, and now it’s a race to try to find out who that person has infected.”

On Tuesday, the CDC offered its most serious warning to date that the United States should expect and prepare for the coronavirus to become a more widespread health issue.

“Ultimately, we expect we will see coronavirus spread in this country,” said Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases. “It’s not so much a question of if, but a question of when.”

According to the CDC’s latest count Wednesday morning, 59 U.S. residents have tested positive for the new strain of coronavirus — 42 of whom are repatriated citizens from a Diamond Princess cruise. That number has grown by two since Messonnier’s last count Tuesday, although the CDC was not immediately available to offer details on the additional cases.

More than 82,000 cases of coronavirus have been reported globally, and more than 2,700 people have died, with the majority in mainland China, the epicenter of the outbreak.

But public health leaders have repeatedly reminded residents that the health risk from the novel coronavirus to the general public remains low.

“While COVID-19 has a high transmission rate, it has a low mortality rate,” the state Department of Public Health said in a statement Wednesday. “From the international data we have, of those who have tested positive for COVID-19, approximately 80% do not exhibit symptoms that would require hospitalization. There have been no confirmed deaths related to COVID-19 in the United States to date.”

CDC officials have also warned that although the virus is likely to spread in U.S. communities, the flu still poses a greater risk.

Gostin said the news of potential silent transmission does not eliminate the possibility of containing the virus in the U.S. and preventing an outbreak.

“There are few enough cases that we should at least try,” he said. “Most of us are not optimistic that that will be successful, but we’re still in the position to try.”

[ChiliConCarnage]

Originally Posted by Mr_Tomahawk

So no chatter about this vaccine that looks promising....?

Where is Hamas? I need to know if I am allowed to get my hopes up over this news.

It sounds like it's pretty effective. They're hoping to start phase 3 in July.

I read something a few weeks back that painted this company as possibly being shady. They've been around quite sometime and not brought anything out completely. I think it said they'd never been to phase 3 testing with any drug. The govt gave them a bunch of money so hopefully that's a good sign.

[BleedingRed]

Originally Posted by BWillie

But I thought everyone had it already!

tests are not the same as anti-body tests......

[BigCatDaddy]

Originally Posted by BleedingRed

tests are not the same as anti-body tests......

Well, it's BWillie. So you know...

[BWillie]

Originally Posted by BleedingRed

tests are not the same as anti-body tests......

youdontsay.meme

[TLO]

Originally Posted by DaFace

Interesting. So if that was random (I have no idea), that would imply that there are somewhere in the vicinity of 760 people in the city who are currently infected (roughly 1%). How does that compare to the official numbers?

If you signed up, you could get tested. So I assume it was a pretty random population that got the test.

We are at 520 infections total. But that goes back to when we first started counting in March and also includes those who have recovered/died.

[DaFace]

Originally Posted by TLO

If you signed up, you could get tested. So I assume it was a pretty random population that got the test.

We are at 520 infections total. But that goes back to when we first started counting in March and also includes those who have recovered/died.

Eh, if it was voluntary, that's likely not very random. Chances are people who had had symptoms (even mild) would be more likely to get tested, for example.

Still, it doesn't sound like a HUGE number of people who have gone undetected.

[TLO]

Originally Posted by DaFace

Eh, if it was voluntary, that's likely not very random. Chances are people who had had symptoms (even mild) would be more likely to get tested, for example.

Still, it doesn't sound like a HUGE number of people who have gone undetected.

I'm not sure how you factor this in, but somewhere between 250-300 of those infections were at the meat packing plant that had the outbreak.

I'm glad to see that doesn't appear to be having a huge impact on the rest of the community. (Unless I'm interpreting this wrong)

['Hamas' Jenkins]

Moderna Vaccine Info:

*Two doses were given, four weeks apart, in differing strengths
*Vaccine recipients expressed levels of antibodies seen in patients that had recovered from COVID-19 by day 43
*However, they claim that data on neutralizing antibodies are only available for eight total patients, which is an exceptionally small sample size
*The highest dose (250 micrograms) is likely too high

This is a Phase I trial, which is really only designed for understanding safety. They've started the groundwork for Phase II and Phase III, but that data will take much longer to come in, because not only are you going to be following patients for safety, but efficacy.

Phase I trials fail at the highest rate (over 85% of the time)
Phase II trials fail around 70% of the time
Phase III trials fail 40% of the time

Be hopeful, but patient. This is why the Gates Foundation is helping fund several candidates at once. It insulates you against an extremely high failure rate.

[Mr_Tomahawk]

Originally Posted by 'Hamas' Jenkins

Moderna Vaccine Info:

*Two doses were given, four weeks apart, in differing strengths
*Vaccine recipients expressed levels of antibodies seen in patients that had recovered from COVID-19 by day 43
*However, they claim that data on neutralizing antibodies are only available for eight total patients, which is an exceptionally small sample size
*The highest dose (250 micrograms) is likely too high

This is a Phase I trial, which is really only designed for understanding safety. They've started the groundwork for Phase II and Phase III, but that data will take much longer to come in, because not only are you going to be following patients for safety, but efficacy.

Phase I trials fail at the highest rate (over 85% of the time)
Phase II trials fail around 70% of the time
Phase III trials fail 40% of the time

Be hopeful, but patient. This is why the Gates Foundation is helping fund several candidates at once. It insulates you against an extremely high failure rate.

There it is.

Thank you sir.

[POND_OF_RED]

Originally Posted by 'Hamas' Jenkins

This is why the Gates Foundation is helping fund several candidates at once. It insulates you against an extremely high failure rate.

Now it makes sense why Gates is involved. He’s been working through failures for awhile now.

[ChiliConCarnage]

Originally Posted by 'Hamas' Jenkins

Moderna Vaccine Info:

Phase I trials fail at the highest rate (over 85% of the time)
Phase II trials fail around 70% of the time
Phase III trials fail 40% of the time

Be hopeful, but patient. This is why the Gates Foundation is helping fund several candidates at once. It insulates you against an extremely high failure rate.

That’s interesting on the failure rates. Thanks.

[Kidd Lex]

Originally Posted by 'Hamas' Jenkins

Moderna Vaccine Info:

*Two doses were given, four weeks apart, in differing strengths
*Vaccine recipients expressed levels of antibodies seen in patients that had recovered from COVID-19 by day 43
*However, they claim that data on neutralizing antibodies are only available for eight total patients, which is an exceptionally small sample size
*The highest dose (250 micrograms) is likely too high

This is a Phase I trial, which is really only designed for understanding safety. They've started the groundwork for Phase II and Phase III, but that data will take much longer to come in, because not only are you going to be following patients for safety, but efficacy.

Phase I trials fail at the highest rate (over 85% of the time)
Phase II trials fail around 70% of the time
Phase III trials fail 40% of the time

Be hopeful, but patient. This is why the Gates Foundation is helping fund several candidates at once. It insulates you against an extremely high failure rate.

Great info as always. One concerning thing I read today about the Oxford vaccine was that the vaccinated monkeys that were inoculated with Covid did indeed get Covid, just an extremely mild version of it versus the monkeys who didn’t get vaccinated who all ended up with viral pneumonia. Now it’s great to turn a bad disease into a cold, but the goal for any vaccine should be immunity at this point, or we will be living with Covid forever. I did see though that the Oxford viral load introduced was huge, and the amount of vaccine used wasn’t. So under different conditions or with booster shots the Oxford vaccine could still be a viable immunity option. I also should note the Oxford and Moderna vaccines are using different approaches, and the Moderna one although early looks promising.

Link regarding Oxford critique:

https://blogs.sciencemag.org/pipelin...avirus-vaccine

[tyecopeland]

My mom got pneumonia last month but didn't get tested for covid. My father in law got pneumonia and was tested for covid yesterday- result negative.

[TLO]

Looks like we're coming in at about 1000 deaths today.

[petegz28]

Courts are starting to get involved more and more it seems. Something tells me the CA lock down will follow suit.

Judge tosses out Oregon's coronavirus restrictions

SALEM, Ore. (AP) — A county judge has declared Oregon Gov. Kate Brown’s coronavirus restrictions “null and void” because she didn’t have her emergency orders approved by the Legislature following 28 days.

Baker County Circuit Judge Matthew Shirtcliff made the ruling Monday in a lawsuit brought churches who had sued saying the social-distancing directives were unconstitutional.

The suit had also argued that emergency powers only last for a month and after that Brown would have needed legislative approval. The judge agreed.

Brown said she would immediately appeal the ruling to the state Supreme Court to try to keep the emergency orders in effect.

“This will ensure we can continue to safeguard the health of all Oregonians — including frontline health care workers, those living in nursing homes, workers in agriculture and food processing plants, and Oregonians with underlying health conditions –– while the legal process moves forward,” Brown said.

Ray Hacke, the attorney who represented the plaintiffs in the case, said in a phone interview Monday the ruling invalidates Brown’s ban on churches gathering for worship but also invalidates the entire stay-at-home order, Hacke said.

Common Sense intervened after the Sacramento-based Pacific Justice Institute filed the case earlier this month on behalf of Oregon businesses, expanding the scope, he said.

“The stay-at-home order is no longer in effect. It is invalidated. If people want to get their haircut, they can. They can leave their home for any reason whether it’s deemed essential in the eye of the state or not,” he said.

He added that the ruling was a vindication not just for freedom of religion, but for all Oregonians’ freedoms.

“Praise God. I’m excited, and I’m glad that the judge saw that there are limitations on the governor’s power, even in the midst of emergencies,” he said.

https://www.msn.com/en-us/news/us/ju...?ocid=msedgntp