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Old 02-26-2020, 10:28 PM  
JakeF JakeF is offline
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***NON-POLITICAL COVID-19 Discussion Thread***

A couple of reminders...

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Originally Posted by Bwana View Post
Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.
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People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Last edited by Bearcat; 03-25-2020 at 08:56 AM.. Reason: adding spoiler tag
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Old 08-24-2020, 06:45 AM   #43456
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It’s not two different strains. Technicality wise maybe But it’s different lineages of the same strain.

Also the second time they caught it they were asymptomatic and only found thru screening
They say the strain from the first infection was completely different than the second and not from the same lineage. The good news is he was asymptomatic the 2nd time unlike the first. The bad news is he got reinfected and they don't believe herd immunity will eliminate covid and that it will linger around like other coronaviruses. We will all have to probably take a vaccine every year for this I imagine.

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Old 08-24-2020, 06:56 AM   #43457
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What is interesting about the strains is that the first one is closely associated with what we are seeing here in the US and the patient had to be hospitalized but the other strain was more closely associated with England\Switzerland.

Makes me wonder now if we got the worse strain which is why we are seeing so many cases\deaths\hospitalizations and other countries aren't.
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Old 08-24-2020, 07:41 AM   #43458
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Quote:
Originally Posted by dirk digler View Post
They say the strain from the first infection was completely different than the second and not from the same lineage. The good news is he was asymptomatic the 2nd time unlike the first. The bad news is he got reinfected and they don't believe herd immunity will eliminate covid and that it will linger around like other coronaviruses. We will all have to probably take a vaccine every year for this I imagine.

We have HI to the common cold. It doesn't mean that you won't get it again though.

Just in this case he/she had neutralizing immunity to make the 2nd infection asymptomatic.

Calm down
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Old 08-24-2020, 07:44 AM   #43459
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Sars Cov 2 will never be eliminated from circulation. We all need to understand that.
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Old 08-24-2020, 07:44 AM   #43460
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Originally Posted by dirk digler View Post
What is interesting about the strains is that the first one is closely associated with what we are seeing here in the US and the patient had to be hospitalized but the other strain was more closely associated with England\Switzerland.

Makes me wonder now if we got the worse strain which is why we are seeing so many cases\deaths\hospitalizations and other countries aren't.
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Old 08-24-2020, 07:46 AM   #43461
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It's apparently a mutation in ORF8 which would theoretically help it evade an immune response.

So like I said, technically a mutated strain but still the same "bug". Usually, the mutated strains are gonna be less virulent/infectious so again, I don't think this is abnormal or anything to get up in arms about.
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Old 08-24-2020, 08:05 AM   #43462
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Originally Posted by O.city View Post
Sars Cov 2 will never be eliminated from circulation. We all need to understand that.

Yeah that’s been obvious from the beginning. There’s a good chance many current coronaviruses started out as localized pandemics as well. I think people underestimate how often things like this have occurred throughout history.
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Old 08-24-2020, 08:08 AM   #43463
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Originally Posted by mr. tegu View Post
Yeah that’s been obvious from the beginning. There’s a good chance many current coronaviruses started out as localized pandemics as well. I think people underestimate how often things like this have occurred throughout history.
At one point, every current virus did. It's how they work.

It'll eventually go endemic.

Yes, inevitably, we'll have people who will get it again. It's the way these things go. But, if you have a normal functioning immune system, you'll have recognition and likely your 2nd one will be very mild or asymptomatic. Look at this 2nd infection. It was attenuated by the immune system and the patient remains asymptomatic. Thats whats supposed to happen.

I'm not sure this really says much about vaccines as well.

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Old 08-24-2020, 08:25 AM   #43464
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Heres a good breakdown.

I was also wrong on the initial HI claim to the common cold, so I'm gonna take my lumps on that one
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Old 08-24-2020, 08:50 AM   #43465
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Quote:
Originally Posted by O.city View Post
We have HI to the common cold. It doesn't mean that you won't get it again though.

Just in this case he/she had neutralizing immunity to make the 2nd infection asymptomatic.

Calm down
Quote:
Originally Posted by O.city View Post
Sars Cov 2 will never be eliminated from circulation. We all need to understand that.
As I said we will probably have to add the Covid vaccine to our yearly shot regiment. Depending on which vaccine we get it may or may not stop it completely but hopefully will give us enough protection to have very mild symptoms. The Moderna vaccine may be good enough to completely stop it since it is using mRNA but only time will tell.
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Old 08-24-2020, 09:01 AM   #43466
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Quote:
Originally Posted by O.city View Post
We have HI to the common cold. It doesn't mean that you won't get it again though.

Just in this case he/she had neutralizing immunity to make the 2nd infection asymptomatic.

Calm down
We do?
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Old 08-24-2020, 09:04 AM   #43467
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We do?
So you don't think everybody has had the common cold?
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Old 08-24-2020, 09:06 AM   #43468
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So you don't think everybody has had the common cold?
Yes, everyone has. Now, where's the large scale (herd) immunity to it?
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Old 08-24-2020, 09:09 AM   #43469
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Yes, everyone has. Now, where's the large scale (herd) immunity to it?
Immunity is measured in levels (sort of) though. In this case, the patient had enough immunity to sterilize the infection with no symptoms. If we tested for other things we have immunity to, I'm guessing we'd find alot of asymptomatic patients carrying.
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Old 08-24-2020, 09:13 AM   #43470
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I'm gonna wait though, until the whole amount of info is analyzed here. If the patient didn't seroconvert the first time, that would explain some things and would tend to be more of an outlier on reinfection as most people mount one.

You've also got n=1 here so, lets not get to far ahead of ourselves.
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