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Old 02-26-2020, 10:28 PM  
JakeF JakeF is offline
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***NON-POLITICAL COVID-19 Discussion Thread***

A couple of reminders...

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Originally Posted by Bwana View Post
Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.
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Originally Posted by Dartgod View Post
People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Last edited by Bearcat; 03-25-2020 at 08:56 AM.. Reason: adding spoiler tag
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Old 06-16-2020, 06:24 AM   #35071
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https://uk.reuters.com/article/uk-he...-idUKKBN23N1WT

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LONDON (Reuters) - Giving low doses of the generic steroid drug dexamethasone to patients admitted to hospital with COVID-19 reduced death rates by around a third among those with the most severe cases of infection, trial data showed on Tuesday.
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Old 06-16-2020, 06:33 AM   #35072
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I was just coming to post that

Good news for sure as that’s easily accessible
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Old 06-16-2020, 07:21 AM   #35073
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Quote:
Originally Posted by O.city View Post
I was just coming to post that

Good news for sure as that’s easily accessible
Man there are some people going off this morning. Jim Cramer on CNBC was livid because his doctors actually prevented him from taking steroids "in case he had to take them for Covid".

So there were obviously some on the medical community that were already onto this.

That all being said this appears to be for severe cases only by still it's great news. Also couple this with the study that said "statins" might be a very good treatment as it reduces the chance for clotting and treats this is a blood\circulatory problem as opposed to a respiratory problem.
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Old 06-16-2020, 07:29 AM   #35074
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Quote:
Originally Posted by petegz28 View Post
Man there are some people going off this morning. Jim Cramer on CNBC was livid because his doctors actually prevented him from taking steroids "in case he had to take them for Covid".

So there were obviously some on the medical community that were already onto this.

That all being said this appears to be for severe cases only by still it's great news. Also couple this with the study that said "statins" might be a very good treatment as it reduces the chance for clotting and treats this is a blood\circulatory problem as opposed to a respiratory problem.
Was he trying to get some sweet gainz but was prevented?
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Old 06-16-2020, 07:33 AM   #35075
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Quote:
Originally Posted by ChiliConCarnage View Post
Does anyone have the full study, because that Reuters article is not precise in its wording. The study dose was 6mg. Five mg of prednisone is equivalent to 0.75 mg of dexamethasone, which means that the study dose is equivalent to 40mg of predinose a day. That's not pulse dosing for organ rejection, but it's also not a "low" dose.

And before we even get started on "give this to everyone", this is not something you would want to take prophylactically. If you take corticosteroids for more than a week you begin to experience adrenal suppression due to the exogenous source of corticosteroids (and there are many other side effects as well).
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Old 06-16-2020, 07:39 AM   #35076
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Quote:
Originally Posted by 'Hamas' Jenkins View Post
Does anyone have the full study, because that Reuters article is not precise in its wording. The study dose was 6mg. Five mg of prednisone is equivalent to 0.75 mg of dexamethasone, which means that the study dose is equivalent to 40mg of predinose a day. That's not pulse dosing for organ rejection, but it's also not a "low" dose.

And before we even get started on "give this to everyone", this is not something you would want to take prophylactically. If you take corticosteroids for more than a week you begin to experience adrenal suppression due to the exogenous source of corticosteroids (and there are many other side effects as well).
Articles about that point out that the more ill the more effective the results. They indicated the treatment is of no use to mildly ill so prophylactic use would not be a consideration.
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Old 06-16-2020, 07:49 AM   #35077
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Quote:
Originally Posted by kgrund View Post
Articles about that point out that the more ill the more effective the results. They indicated the treatment is of no use to mildly ill so prophylactic use would not be a consideration.
That's how I understand it. It is only for severe cases and not to be used as a prophylactic.
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Old 06-16-2020, 07:51 AM   #35078
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Quote:
The results suggest the drug should immediately become standard care in patients with severe cases of the pandemic disease, said the researchers who led the trials.
“This is a result that shows that if patients who have Covid-19 and are on ventilators or are on oxygen are given dexamethasone, it will save lives, and it will do so at a remarkably low cost,” said Martin Landray, an Oxford University professor co-leading the trial, known as the RECOVERY trial.
https://www.cnbc.com/2020/06/16/ster...-19-trial.html
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Old 06-16-2020, 08:24 AM   #35079
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Steroids IIRC, are essentially an immune suppressant. So theoretically, with the cytokine storm they would help.
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Old 06-16-2020, 08:54 AM   #35080
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Old 06-16-2020, 08:55 AM   #35081
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Old 06-16-2020, 08:55 AM   #35082
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The south doesn't seem to be handling this well.
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Old 06-16-2020, 09:26 AM   #35083
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Revised total:

201,129 COVID-19 deaths projected by October 1, 2020
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Old 06-16-2020, 10:09 AM   #35084
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Arkansas has a shit pot of poultry processing plants which supposedly is driving that curve up. One of my friends from Dodge City said that meat processing workers are taking a fever reducer before work if they are sick in order to trick the daily temperature readings.

Little Rock is staying relatively stable and safe. I think the governor said yesterday that Little Rock had ~20 new cases a day. I think its interesting to note that Arkansas never implemented a stay-at-home order.
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Old 06-16-2020, 11:30 AM   #35085
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New numbers released by the US Centers for Disease Control and Prevention offer a comprehensive picture of who in the United States has been diagnosed with Covid-19 and how they fared.

The latest figures confirm that older people, minorities and those with preexisting health conditions are at the highest risk of death.

There was a total of 1,761,503 cases of Covid-19 and 103,700 related deaths in the country between January 22 (when the first case was confirmed) and May 30, according to the surveillance report, published in the CDC's Morbidity and Mortality Weekly Report. The data come from local, state and federal sources and is consistent with those reported through the Johns Hopkins University Coronavirus Resource Center.

Overall, 184,673 (14%) patients were hospitalized, 29,837 (2%) were admitted to an intensive care unit (ICU), and 71,116 (5%) died. Hospitalizations are six times higher and deaths are 12 times higher among those who reported underlying conditions. The most common underlying conditions were cardiovascular disease (32%), diabetes (30%) and chronic lung disease (18%).

The report found that the incidence rate is 403.6 cases per 100,000, with men and women getting sick at almost the same rate. But the percentages of males who were hospitalized (16%), admitted to the ICU (3%) and who died (6%) were higher than were those for females (12%, 2% and 5%, respectively).

The rate was highest among people 80 and older and lowest among children 9 and younger. But the relationship between age and incidence rate was not a straight line: It was higher among peoples age 40-49 years and 50-59 years than among those age 60-69 years and 70-79 years.

Among cases with known race and ethnicity, 33% were Hispanic, 22% were black, and 1.3% were American Indian or Alaska Native. The report notes that "these findings suggest that persons in these groups, who account for 18%, 13%, and 0.7% of the U.S. population, respectively, are disproportionately affected by the COVID-19 pandemic."


CDC received notification of the first case of laboratory-confirmed COVID-19 in the United States on January 22, 2020. As of May 30, an aggregate 1,761,503 U.S. COVID-19 cases and 103,700 deaths had been reported (Figure). The 7-day moving average number of new daily cases peaked on April 12 (31,994) and deaths peaked on April 21 (2,856). As of May 30, the 7-day moving average numbers of new cases were 19,913 per day and deaths were 950 per day.
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