Busted ankle and Opioids

[Naptown Chief]

Originally Posted by oldman

I had a similar injury several years ago. Oxy wasn't widely available until later, so they kept trying to push the Tylenol 3s on me. No thanks, I'll just use ibuprofen. I took 800 mg 3 times a day until the boot came off and then slowly worked down to 400 once a day. I've just seen too many people get dependent on that stuff. I don't think it's weakness on the part of those that get hooked, it's a physical addiction that Purude Pharma is all too glad to supply.

They actually started me on Tylenol 3, then 4, before being bumped to hydrocodone 5, 7.5, and ultimately the 10s. Even though the opiate dosage is higher in the hydrocodone, I felt substantially more lethargic on the codeine

['Hamas' Jenkins]

Originally Posted by dwwataz

They actually started me on Tylenol 3, then 4, before being bumped to hydrocodone 5, 7.5, and ultimately the 10s. Even though the opiate dosage is higher in the hydrocodone, I felt substantially more lethargic on the codeine

There's a chance you could be an ultra-rapid metabolizer of CYP 2D6. Codeine is a prodrug that is in converted to morphine. A small subset of the population has more of those specific enzymes than others. If so, a "normal" dose of codeine can actually be much higher for the person in question.

This is why codeine is not given to children anymore.

[rabblerouser]

Originally Posted by Naptown Chief

They actually started me on Tylenol 3, then 4, before being bumped to hydrocodone 5, 7.5, and ultimately the 10s. Even though the opiate dosage is higher in the hydrocodone, I felt substantially more lethargic on the codeine

Back in the 80s and 90s they used to give that shit out like candy. It was like a reward for going to the doctor.

I remember being like 10 and and I was having a little allergy issue, nothing big, like a scratch in my throat. My mom goes "sounds like you need some cough syrup" and called the HMO up "yes, my son is in need of an expectorant, yeah...something with Codeine...thanks."

And she went picked up this GIANT bottle of syzzurp. Without me ever seeing or even talking to the doctor. Huge. Tall boy. And I'm like, "why is my mom drinking my cough syrup?"

About an hour later and a couple decent swigs of my own, I was cleaning my room and listening to Led Zeppelin I on cassette (remember those?) and all the sudden, this overwhelming urge to lay down came over me...and as I was laying in bed, listening to Zep and staring at the posters of GNR, Mötley Crüe, and The Black Crowes on my wall (pre-grunge era), I realized exactly why my mom was drinking my cough syrup - because it was DELICIOUS.

[sd4chiefs]

I only took Opioids once about 5 years ago just before I when to bed. I spent the next four hours with major hiccups.

[rabblerouser]

Originally Posted by sd4chiefs

I only took Opioids once about 5 years ago just before I when to bed. I spent the next four hours with major hiccups.