***NON-POLITICAL COVID-19 Discussion Thread***

[JakeF]

A couple of reminders...

Originally Posted by Bwana

Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.

Originally Posted by Dartgod

People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Apparently the CoronaVirus can survive on a inanimate objects, such as door knobs, for 9 days.

California coronavirus case could be first spread within U.S. community, CDC says
By SOUMYA KARLAMANGLA, JACLYN COSGROVE
FEB. 26, 2020 8:04 PM

The Centers for Disease Control and Prevention is investigating what could be the first case of novel coronavirus in the United States involving a patient in California who neither recently traveled out of the country nor was in contact with someone who did.

“At this time, the patient’s exposure is unknown. It’s possible this could be an instance of community spread of COVID-19, which would be the first time this has happened in the United States,” the CDC said in a statement. “Community spread means spread of an illness for which the source of infection is unknown. It’s also possible, however, that the patient may have been exposed to a returned traveler who was infected.”

The individual is a resident of Solano County and is receiving medical care in Sacramento County, according to the state Department of Public Health.

The CDC said the “case was detected through the U.S. public health system — picked up by astute clinicians.”

Officials at UC Davis Medical Center expanded on what the federal agency might have meant by that in an email sent Wednesday, as reported by the Davis Enterprise newspaper.

The patient arrived at UC Davis Medical Center from another hospital Feb. 19 and “had already been intubated, was on a ventilator, and given droplet protection orders because of an undiagnosed and suspected viral condition,” according to an email sent by UC Davis officials that was obtained by the Davis Enterprise.

The staff at UC Davis requested COVID-19 testing by the CDC, but because the patient didn’t fit the CDC’s existing criteria for the virus, a test wasn’t immediately administered, according to the email. The CDC then ordered the test Sunday, and results were announced Wednesday. Hospital administrators reportedly said in the email that despite these issues, there has been minimal exposure at the hospital because of safety protocols they have in place.

A UC Davis Health spokesperson declined Wednesday evening to share the email with The Times.

Since Feb. 2, more than 8,400 returning travelers from China have entered California, according to the state health department. They have been advised to self-quarantine for 14 days and limit interactions with others as much as possible, officials said.

“This is a new virus, and while we are still learning about it, there is a lot we already know,” Dr. Sonia Angell, director of the California Department of Public Health, said in a statement. “We have been anticipating the potential for such a case in the U.S., and given our close familial, social and business relationships with China, it is not unexpected that the first case in the U.S. would be in California.”

It is not clear how the person became infected, but public health workers could not identify any contacts with people who had traveled to China or other areas where the virus is widespread. That raises concern that the virus is spreading in the United States, creating a challenge for public health officials, experts say.

“It’s the first signal that we could be having silent transmission in the community,” said Lawrence Gostin, director of the World Health Organization Collaborating Center on National and Global Health Law. “It probably means there are many more cases out there, and it probably means this individual has infected others, and now it’s a race to try to find out who that person has infected.”

On Tuesday, the CDC offered its most serious warning to date that the United States should expect and prepare for the coronavirus to become a more widespread health issue.

“Ultimately, we expect we will see coronavirus spread in this country,” said Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases. “It’s not so much a question of if, but a question of when.”

According to the CDC’s latest count Wednesday morning, 59 U.S. residents have tested positive for the new strain of coronavirus — 42 of whom are repatriated citizens from a Diamond Princess cruise. That number has grown by two since Messonnier’s last count Tuesday, although the CDC was not immediately available to offer details on the additional cases.

More than 82,000 cases of coronavirus have been reported globally, and more than 2,700 people have died, with the majority in mainland China, the epicenter of the outbreak.

But public health leaders have repeatedly reminded residents that the health risk from the novel coronavirus to the general public remains low.

“While COVID-19 has a high transmission rate, it has a low mortality rate,” the state Department of Public Health said in a statement Wednesday. “From the international data we have, of those who have tested positive for COVID-19, approximately 80% do not exhibit symptoms that would require hospitalization. There have been no confirmed deaths related to COVID-19 in the United States to date.”

CDC officials have also warned that although the virus is likely to spread in U.S. communities, the flu still poses a greater risk.

Gostin said the news of potential silent transmission does not eliminate the possibility of containing the virus in the U.S. and preventing an outbreak.

“There are few enough cases that we should at least try,” he said. “Most of us are not optimistic that that will be successful, but we’re still in the position to try.”

[dirk digler]

Here you go O.City

Just out @nature: 35% of healthy people (#SARSCoV2 seronegative) have reactive SARSCoV2 CD4 T cells to spike protein, presumably d/t cross-reactive coronavirus exposurehttps://t.co/Xt5tuULuyU
Important implications for explaining variable response to infections & vaccine trials

— Eric Topol (@EricTopol) July 29, 2020

[O.city]

Well there you go

That immediately changes a lot of the early models

[O.city]

That also changes some of the serology studies that show just antibodies

[dlphg9]

Originally Posted by TLO

Someone from reddit who seems to know what they're talking about.

I worked in a hospital lab for 6 years and an elevated Troponin I was a critical high that would get a patient a quick flight to a KC hospital because they were having a MI. Troponin I levels raise due to heart damage. There is another condition that raises TNI, but I think it's fairly rare and I cant even think of what it's called.

That info may be wrong, but 2 different lab managers told me that. Maybe they were full of shit.

[DaFace]

Originally Posted by dirk digler

Here you go O.City

Just out @nature: 35% of healthy people (#SARSCoV2 seronegative) have reactive SARSCoV2 CD4 T cells to spike protein, presumably d/t cross-reactive coronavirus exposurehttps://t.co/Xt5tuULuyU
Important implications for explaining variable response to infections & vaccine trials

— Eric Topol (@EricTopol) July 29, 2020

I really despise headlines like that. It's based on a small sample of people in Berlin from what I can tell, so generalizing it to "healthy people" broadly and giving it an exact percentage is really misleading.

But that said, it's encouraging and suggests that there's almost certainly something to the idea that "natural immunity" is a thing and may be fairly widespread.

[MahomesMagic]

Originally Posted by O.city

That also changes some of the serology studies that show just antibodies

Which is why Covid seems to break off around 20%seroprevalence.

Sucharit Bhakdi, microbiology and infectious diseases expert in Germany stated he thought 90% would already have prior immunity.

Karl Friston, running computer models, said it looked like 80% of Britain was "out of the game".

Sunetra Gupta, epidemiology at Oxford, thought 60%+ had prior immunity.

Beda Stadler, Immunology at the University of Bern, thinks 70%+ were already immune.

[dirk digler]

Originally Posted by DaFace

I really despise headlines like that. It's based on a small sample of people in Berlin from what I can tell, so generalizing it to "healthy people" broadly and giving it an exact percentage is really misleading.

But that said, it's encouraging and suggests that there's almost certainly something to the idea that "natural immunity" is a thing and may be fairly widespread.

It was a really small study but I know OCity would like it. It would be awesome if true but not really buying it yet at least for us in the USA. Maybe in Southeast Asia where they have more exposure to SARS and MERS and other crazy things.

[Pasta Little Brioni]

Originally Posted by Chief Roundup

If some of you get the boot just know you have it coming. Although I have noticed there have been several political posts in multiple threads tonight.

Sent from my SM-G973U1 using Tapatalk

There was a hockey game on, so they were safe

[DaFace]

Originally Posted by Pasta Giant Meatball

There was a hockey game on, so they were safe

Contrary to popular opinion, we've really been very hesitant to boot people from the thread since probably mid-April. After that, people have pushed the limits here and there, and we've booted people who just keep doing it over and over again, but overall we've tried to let minor things go.

[Pasta Little Brioni]

Originally Posted by DaFace

Contrary to popular opinion, we've really been very hesitant to boot people from the thread since probably mid-April. After that, people have pushed the limits here and there, and we've booted people who just keep doing it over and over again, but overall we've tried to let minor things go.

Yeah it's been surprisingly well behaved for the most part

[DaFace]

Originally Posted by dirk digler

It was a really small study but I know OCity would like it. It would be awesome if true but not really buying it yet at least for us in the USA. Maybe in Southeast Asia where they have more exposure to SARS and MERS and other crazy things.

While this stuff is way beyond any expertise I could claim to have, my understanding is that there are seven widespread coronaviruses, and four of them are from common colds. (The rest of them are SARS and MERS.) I don't know any strong reason that this cross immunity couldn't be driven by the colds as much as SARS and MERS, so there's really pretty good hope that there's a lot of cross immunity worldwide.

More data is needed, but overall, between vaccine progress, improved therapeutics, and cross immunity, I'm really hopeful that live can be mostly back to normal by the end of the year. Fingers crossed.

[O.city]

If you get some crows immunity from SARS or mers you’ll get it from the common cold ones.

Again, there’s gotta be something that’s bringing these curves down this quick like they are. If it’s truly novel and We’re all able to get it, you’d not get curves down like that.

[Discuss Thrower]

Whatever Japan is doing isn't working.

[O.city]

Originally Posted by Discuss Thrower

Whatever Japan is doing isn't working.

Basically everywhere that was successful early is having issues now.

[petegz28]

Originally Posted by O.city

Basically everywhere that was successful early is having issues now.

Seems that way.....