***NON-POLITICAL COVID-19 Discussion Thread***

[JakeF]

A couple of reminders...

Originally Posted by Bwana

Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.

Originally Posted by Dartgod

People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Apparently the CoronaVirus can survive on a inanimate objects, such as door knobs, for 9 days.

California coronavirus case could be first spread within U.S. community, CDC says
By SOUMYA KARLAMANGLA, JACLYN COSGROVE
FEB. 26, 2020 8:04 PM

The Centers for Disease Control and Prevention is investigating what could be the first case of novel coronavirus in the United States involving a patient in California who neither recently traveled out of the country nor was in contact with someone who did.

“At this time, the patient’s exposure is unknown. It’s possible this could be an instance of community spread of COVID-19, which would be the first time this has happened in the United States,” the CDC said in a statement. “Community spread means spread of an illness for which the source of infection is unknown. It’s also possible, however, that the patient may have been exposed to a returned traveler who was infected.”

The individual is a resident of Solano County and is receiving medical care in Sacramento County, according to the state Department of Public Health.

The CDC said the “case was detected through the U.S. public health system — picked up by astute clinicians.”

Officials at UC Davis Medical Center expanded on what the federal agency might have meant by that in an email sent Wednesday, as reported by the Davis Enterprise newspaper.

The patient arrived at UC Davis Medical Center from another hospital Feb. 19 and “had already been intubated, was on a ventilator, and given droplet protection orders because of an undiagnosed and suspected viral condition,” according to an email sent by UC Davis officials that was obtained by the Davis Enterprise.

The staff at UC Davis requested COVID-19 testing by the CDC, but because the patient didn’t fit the CDC’s existing criteria for the virus, a test wasn’t immediately administered, according to the email. The CDC then ordered the test Sunday, and results were announced Wednesday. Hospital administrators reportedly said in the email that despite these issues, there has been minimal exposure at the hospital because of safety protocols they have in place.

A UC Davis Health spokesperson declined Wednesday evening to share the email with The Times.

Since Feb. 2, more than 8,400 returning travelers from China have entered California, according to the state health department. They have been advised to self-quarantine for 14 days and limit interactions with others as much as possible, officials said.

“This is a new virus, and while we are still learning about it, there is a lot we already know,” Dr. Sonia Angell, director of the California Department of Public Health, said in a statement. “We have been anticipating the potential for such a case in the U.S., and given our close familial, social and business relationships with China, it is not unexpected that the first case in the U.S. would be in California.”

It is not clear how the person became infected, but public health workers could not identify any contacts with people who had traveled to China or other areas where the virus is widespread. That raises concern that the virus is spreading in the United States, creating a challenge for public health officials, experts say.

“It’s the first signal that we could be having silent transmission in the community,” said Lawrence Gostin, director of the World Health Organization Collaborating Center on National and Global Health Law. “It probably means there are many more cases out there, and it probably means this individual has infected others, and now it’s a race to try to find out who that person has infected.”

On Tuesday, the CDC offered its most serious warning to date that the United States should expect and prepare for the coronavirus to become a more widespread health issue.

“Ultimately, we expect we will see coronavirus spread in this country,” said Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases. “It’s not so much a question of if, but a question of when.”

According to the CDC’s latest count Wednesday morning, 59 U.S. residents have tested positive for the new strain of coronavirus — 42 of whom are repatriated citizens from a Diamond Princess cruise. That number has grown by two since Messonnier’s last count Tuesday, although the CDC was not immediately available to offer details on the additional cases.

More than 82,000 cases of coronavirus have been reported globally, and more than 2,700 people have died, with the majority in mainland China, the epicenter of the outbreak.

But public health leaders have repeatedly reminded residents that the health risk from the novel coronavirus to the general public remains low.

“While COVID-19 has a high transmission rate, it has a low mortality rate,” the state Department of Public Health said in a statement Wednesday. “From the international data we have, of those who have tested positive for COVID-19, approximately 80% do not exhibit symptoms that would require hospitalization. There have been no confirmed deaths related to COVID-19 in the United States to date.”

CDC officials have also warned that although the virus is likely to spread in U.S. communities, the flu still poses a greater risk.

Gostin said the news of potential silent transmission does not eliminate the possibility of containing the virus in the U.S. and preventing an outbreak.

“There are few enough cases that we should at least try,” he said. “Most of us are not optimistic that that will be successful, but we’re still in the position to try.”

[TLO]

Originally Posted by O.city

Don't know the reaction. But, thats normal to put the trial on pause. It's how they always do it.

Makes sense I guess. Hopefully they aren't down too long, and hopefully the reaction wasn't too bad.

[KCUnited]

And that’s likely for just one of 100 possible side effects they rapidly rattle off at the end of those super cringe pharmaceutical commercials.

[O.city]

Originally Posted by TLO

Makes sense I guess. Hopefully they aren't down too long, and hopefully the reaction wasn't too bad.

Could be something very trivial, or could be very serious. Hard to know.

IIRC, the ChaDOx vaccine had a fair amount of mild side effects in phase 1 and 2 so that would make sense.

[sedated]

Originally Posted by O.city

Or instead of forcing people, give them the information that they work and encourage them to wear them.

Really? Like that's even realistic at this point? "The" information gets bogged down in BS stories and conspiracy theories.

Hell, a few posts above yours was one about a YouTube video that said infrared thermometers were making kids sick.

[suzzer99]

Originally Posted by O.city

Or instead of forcing people, give them the information that they work and encourage them to wear them.

Force in public health isn't a long term strategy thats going to work.

Which might work fine if mask-wearing was something you do in the privacy of your own home instead of an obvious public choice.

My road trip of anecdotal observation strongly suggests that education doesn't make a difference. If the store doesn't say wear a mask, people don't (at least in Utah and Wyoming). If the store says wear a mask, people do.

Humans are hyper-social animals. People do what the other people around them do basically.

Also you've got the internet where people get to choose which side they want to believe on any issue - and have it instantly validated. The idea of giving people information once an issue becomes politicized is folly imo.

[suzzer99]

Originally Posted by O.city

Orders aren't gonna work.

If everyone would wear them, properly, it would likely make a difference in transmission etc, especially if we could get respirator masks to everyone.

I think mask-wearing is making a big difference. We could have blown up much more than we already did. Most of the big cities wear masks, and most places that don't wear masks have pretty low population density - which means it probably doesn't matter that much.

[O.city]

You guys aren’t wrong

Which is why it’s that much more important to be hyper transparent from the beginning.

People are hyper social and we are expecting what to happen when you co to you sly tell them not to be social and shame them when they are?

This has been basically a crash course in what not to do during a pandemic

[Donger]

https://www.statnews.com/2020/09/08/...nt-in-the-u-k/

large, Phase 3 study testing a Covid-19 vaccine being developed by AstraZeneca and the University of Oxford at dozens of sites across the U.S. has been put on hold due to a suspected serious adverse reaction in a participant in the United Kingdom.

A spokesperson for AstraZeneca, a frontrunner in the race for a Covid-19 vaccine, said in a statement that the company’s “standard review process triggered a pause to vaccination to allow review of safety data.”

It was not immediately clear who placed the hold on the trial, though it is possible it was placed voluntarily by AstraZeneca and not ordered by any regulatory agency. The nature of the adverse reaction and when it happened were also not immediately known, though the participant is expected to recover, according to an individual familiar with the matter.

The spokesperson described the pause as “a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials.” The spokesperson also said that the company is “working to expedite the review of the single event to minimize any potential impact on the trial timeline.”

An individual familiar with the development said researchers had been told the hold was placed on the trial out of “an abundance of caution.” A second individual familiar with the matter, who also spoke on condition of anonymity, said the finding is having an impact on other AstraZeneca vaccine trials underway — as well as on the clinical trials being conducted by other vaccine manufacturers.

Clinical holds are not uncommon, and it’s unclear how long AstraZeneca’s might last. But the progress of the company’s trial — and those of all Covid-19 vaccines in development — are being closely watched given the pressing need for new ways to curb the global pandemic. There are currently nine vaccine candidates in Phase 3 trials. AstraZeneca’s is the first Phase 3 Covid-19 vaccine trial known to have been put on hold.

Researchers running other trials are now looking for similar cases of adverse reactions by combing through databases reviewed by a so-called Data and Safety Monitoring Board, the second person said.

AstraZeneca only began its Phase 3 trial in the U.S. in late August. The U.S. trial is currently taking place at 62 sites across the country, according to clinicaltrials.gov, a government registry, though some have not yet started enrolling participants. Phase 2/3 trials were previously started in the U.K., Brazil, and South Africa.

There are a number of different reactions that can qualify as suspected serious adverse reactions, symptoms that require hospitalization, life-threatening illness and even death. It was also not immediately clear which clinical trial the adverse reaction occurred in, though a clear possibility is the Phase 2/3 trial underway in the U.K.

[suzzer99]

Despite the viral mask meltdowns, if a store says wear a mask, 99% of people do. That's plenty good enough from a spread POV.

It took seatbelt laws to get everyone to wear seatbelts. But when was the last time you even heard of someone getting a seatbelt ticket? Sometimes you have to nudge people.

[sedated]

Originally Posted by suzzer99

It took seatbelt laws to get everyone to wear seatbelts. But when was the last time you even heard of someone getting a seatbelt ticket? Sometimes you have to nudge people.

I know someone that got one a year ago. Granted, it was in south Overland Park where the cops have nothing to do but give BS citations, but they had a "checkpoint" setup (a few cops standing at a 4-way stop looking in everyone's cars)

[htismaqe]

Originally Posted by suzzer99

Despite the viral mask meltdowns, if a store says wear a mask, 99% of people do. That's plenty good enough from a spread POV.

It took seatbelt laws to get everyone to wear seatbelts. But when was the last time you even heard of someone getting a seatbelt ticket? Sometimes you have to nudge people.

About half the people I see wearing masks now aren't wearing them correctly, though.

It's a no-win situation. People aren't putting on masks because they think it works. They're putting on masks to appease the people around them. That's why I see dozens of people at the store with a mask around their mouth while their nose is exposed.

[htismaqe]

Originally Posted by TLO

Ivermectin has my attention now too.

An antiparasitic? For pets?

[suzzer99]

Originally Posted by htismaqe

About half the people I see wearing masks now aren't wearing them correctly, though.

It's a no-win situation. People aren't putting on masks because they think it works. They're putting on masks to appease the people around them. That's why I see dozens of people at the store with a mask around their mouth while their nose is exposed.

At least the nose is aimed down and not straight out into the air and nearby people. It's gotta be better than nothing.

[dirk digler]

Originally Posted by Donger

https://www.statnews.com/2020/09/08/...nt-in-the-u-k/

large, Phase 3 study testing a Covid-19 vaccine being developed by AstraZeneca and the University of Oxford at dozens of sites across the U.S. has been put on hold due to a suspected serious adverse reaction in a participant in the United Kingdom.

A spokesperson for AstraZeneca, a frontrunner in the race for a Covid-19 vaccine, said in a statement that the company’s “standard review process triggered a pause to vaccination to allow review of safety data.”

It was not immediately clear who placed the hold on the trial, though it is possible it was placed voluntarily by AstraZeneca and not ordered by any regulatory agency. The nature of the adverse reaction and when it happened were also not immediately known, though the participant is expected to recover, according to an individual familiar with the matter.

The spokesperson described the pause as “a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials.” The spokesperson also said that the company is “working to expedite the review of the single event to minimize any potential impact on the trial timeline.”

An individual familiar with the development said researchers had been told the hold was placed on the trial out of “an abundance of caution.” A second individual familiar with the matter, who also spoke on condition of anonymity, said the finding is having an impact on other AstraZeneca vaccine trials underway — as well as on the clinical trials being conducted by other vaccine manufacturers.

Clinical holds are not uncommon, and it’s unclear how long AstraZeneca’s might last. But the progress of the company’s trial — and those of all Covid-19 vaccines in development — are being closely watched given the pressing need for new ways to curb the global pandemic. There are currently nine vaccine candidates in Phase 3 trials. AstraZeneca’s is the first Phase 3 Covid-19 vaccine trial known to have been put on hold.

Researchers running other trials are now looking for similar cases of adverse reactions by combing through databases reviewed by a so-called Data and Safety Monitoring Board, the second person said.

AstraZeneca only began its Phase 3 trial in the U.S. in late August. The U.S. trial is currently taking place at 62 sites across the country, according to clinicaltrials.gov, a government registry, though some have not yet started enrolling participants. Phase 2/3 trials were previously started in the U.K., Brazil, and South Africa.

There are a number of different reactions that can qualify as suspected serious adverse reactions, symptoms that require hospitalization, life-threatening illness and even death. It was also not immediately clear which clinical trial the adverse reaction occurred in, though a clear possibility is the Phase 2/3 trial underway in the U.K.

Man that is disappointing. That was the one I was thinking was a sure thing. Hopefully they find it wasn’t related to the vaccine.

[loochy]

Originally Posted by dirk digler

Man that is disappointing. That was the one I was thinking was a sure thing. Hopefully they find it wasn’t related to the vaccine.

It might still be a sure thing. They don't even know what caused the mystery sickness.